Colorectal cancer (CRC) ranks third in the incidences of cancer morbidity and mortality
worldwide. CRC is rather heterogeneous with regard to molecular genetic characteristics …

Background We recently showed that the presence of ERCC1+ CTCs is an independent
predictive biomarker for platinum-resistance and poor prognosis of ovarian cancer. The goal …

BACKGROUND Platinum resistance constitutes one of the most recognized clinical
challenges for ovarian cancer. Notably, the detection of the primary tumor-based excision …

Citrate synthase (CS), one of the key enzymes in the tricarboxylic acid (TCA) cycle, catalyzes
the reaction between oxaloacetic acid and acetyl coenzyme A to generate citrate. Increased …

The present study aimed to investigate the association between excision repair cross-
complementation group 1 (ERCC1) expression and clinical resistance to platinum‑based …

Introduction Oxaliplatin is part of pancreatic cancer therapy in the FOLFIRINOX or
GEMOX/XELOX regimen. DNA damage repair is one of the factors responsible for …

Disease progression is a major problem in ovarian cancer. There are very few treatment
options for patients with platinum‐resistant ovarian cancer (PROC), and therefore, these …

Objective: This study aimed to comprehensively investigate the correlation of ERCC1
expression and chemosensitivity of ovarian cancer. Methods: The literature on the …

Aims: We conducted a case-control study in a Chinese population to clarify the association
betweenpolymorphisms in ERCC1 and XPD and susceptibility and survival of glioma …

The aim of the study was to investigate the potential mechanisms that interferencing of
excision repair cross-complementing gene 1 (ERCC1) mediated by lentiviral vector in …