Chromatin accessibility profiling methods

L Minnoye, GK Marinov, T Krausgruber, L Pan… - Nature Reviews …, 2021 - nature.com
Chromatin accessibility, or the physical access to chromatinized DNA, is a widely studied
characteristic of the eukaryotic genome. As active regulatory DNA elements are generally …

The evolution of the cancer stem cell state in glioblastoma: emerging insights into the next generation of functional interactions

K Mitchell, K Troike, DJ Silver, JD Lathia - Neuro-oncology, 2021 - academic.oup.com
Cellular heterogeneity is a hallmark of advanced cancers and has been ascribed in part to a
population of self-renewing, therapeutically resistant cancer stem cells (CSCs) …

Alleloscope: Integrative analysis of single cell haplotype-divergent copy number alterations and chromatin accessibility changes reveals novel clonal architecture of …

CY Wu, BT Lau, H Kim, A Sathe, SM Grimes, HP Ji… - bioRxiv, 2020 - biorxiv.org
Cancer progression is driven by both somatic copy number aberrations (CNAs) and
chromatin remodeling, yet little is known about the interplay between these two classes of …