Highlights•A useful reference for quantitative analysis of histone modifications.•Three
general approaches to analyze histone modifications by mass spectrometry.•Analytical …

Over 17,000 papers related to proteomics have been published since our 2011− 2013
review. A subset are true gems reporting amazing applications of proteomics to better …

Lysine acetylation is a reversible posttranslational modification that occurs at thousands of
sites on human proteins. However, the stoichiometry of acetylation remains poorly …

Epigenetics has become a fundamental scientific discipline with various implications for
biology and medicine. Epigenetic marks, mostly DNA methylation and histone post …

The ability of cells to store and rapidly mobilize energy reserves in response to nutrient
availability is essential for survival. Breakdown of carbon stores produces acetyl-CoA …

Normal skeletal muscle metabolism is essential for whole body metabolic homoeostasis and
disruptions in muscle metabolism are associated with a number of chronic diseases …

An experimental route to identify and separate geometric isomers by means of coincident
Coulomb explosion imaging is presented, allowing isomer-resolved photoionization studies …

In eukaryotic organisms, DNA is not free rather present as a highly complex structure called
chromatin. This chapter reviews different posttranslation modifications of histone proteins …

Ion mobility spectrometry (IMS) in conjunction with mass spectrometry (MS) has emerged as
a powerful platform for biological and environmental analyses. An inherent advantage of …

Structurally diverse acylations have been identified as post‐translational modifications
(PTMs) on histone lysine residues, but their functions and regulations remain largely …