The key regulators of the transcriptional response to hypoxia and inflammation (hypoxia
inducible factor, HIF, and nuclear factor-kappa B, NF-κB, respectively) are evolutionarily …

Eleutheroside E (EE) is a primary active component of Acanthopanax senticosus, which has
been reported to inhibit the expression of inflammatory genes, but the underlying …

Background: Exaggerated pulmonary arterial hypertension (PAH) is a hallmark of high-
altitude pulmonary edema (HAPE). The objective of this study was therefore to investigate …

Background: Breast Implant Illness after aesthetic breast augmentation remains a poorly-
defined syndrome. Prior published studies have identified difficulty breathing as a symptom …

Aims Baseline elevated B-type Natriuretic Peptide (BNP) has been found in high altitude
pulmonary edema susceptible population. Exaggerated pulmonary vascular response to …

Background: Travelling to high altitude (HA) presents a risk of the high levels of pulmonary
artery pressure (PAP) at altitude, which is associated with impaired exercise capacity and …

Objective Subclinical life style disease can cause endothelial dysfunction associated with
perfusion abnormalities and reduced vascular compliance. Subclinical elevated beta type …

Swimming exercise at sea level causes a transient decrease in lung diffusing capacity for
carbon monoxide (DLCO). The exposure to hypobaric hypoxia can affect lung gas …

High altitude is a physiologically stressful environment due to oxygen limitation and low
atmospheric pressure. Despite these conditions, over 160 million people live, work, or travel …

To investigate the effects of chronic hypoxia exposure at high altitude on the formation of
pulmonary edema in rats, we randomized rats into normoxic control groups and hypoxic 24 …