Planar polarity describes the coordinated polarisation of cells or structures in the plane of a
tissue. The patterning mechanisms that underlie planar polarity are well characterised in …

Throughout the eukaryotic lineage, small RNA silencing pathways protect the genome
against the deleterious influence of selfish genetic elements such as transposons. In …

Polarized cell behaviors drive axis elongation in animal embryos, but the mechanisms
underlying elongation of many tissues remain unknown. Eggs of Drosophila undergo …

How organ-shaping mechanical imbalances are generated is a central question of
morphogenesis, with existing paradigms focusing on asymmetric force generation within …

Tissues use numerous mechanisms to change shape during development. The Drosophila
egg chamber is an organ-like structure that elongates to form an elliptical egg. During …

Maternally inherited mitochondria and other cytoplasmic organelles play essential roles
supporting the development of early embryos and their germ cells. Using methods that …

Understanding how molecular dynamics leads to cellular behaviours that ultimately sculpt
organs and tissues is a major challenge not only in basic developmental biology but also in …

Epithelial cells use a striking array of morphogenetic behaviors to sculpt organs and body
plans during development. Although it is clear that epithelial morphogenesis is largely …

▪ Abstract Epithelial morphogenesis comprises the various processes by which epithelia
contribute to organ formation and body shape. These complex and diverse events play a …

Wolbachia are widespread maternally transmitted intracellular bacteria that infect most
insect species and are able to alter the reproduction of innumerous hosts. The cellular bases …