Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality. Reperfusion
strategies are the current standard therapy for AMI. However, they may result in paradoxical …

Myocardial infarction is defined as sudden ischemic death of myocardial tissue. In the
clinical context, myocardial infarction is usually due to thrombotic occlusion of a coronary …

How is the heartbeat generated? What controls the strength of contraction of heart muscle?
What are the links between cardiac structure and function? How does our understanding of …

Cardiac troponins are components of the contractual apparatus in cardiac myocytes and are
expressed exclusively in the heart. A number of nonischemic conditions including …

The past two decades have witnessed an explosive growth of knowledge regarding
postischemic myocardial dysfunction or myocardial “stunning.” The purpose of this review is …

How a cell responds to stress is a central problem in cardiovascular biology. Diverse
physiological stresses (eg, heat, hemodynamics, mutant proteins, and oxidative injury) …

In experimental studies in the dog, total proximal coronary artery occlusions of up to 15
minutes result in reversible injury, meaning that the myocytes survive this insult. The 15 …

Case presentation: SB is a 48-year-old man who suffered an acute anterior myocardial
infarction and received fibrinolytic therapy. The patient died 12 hours after reperfusion. KR is …

Background—Matrix metalloproteinases are best recognized for their ability to degrade the
extracellular matrix in both physiological and pathological conditions. However, recent …

On July 2–3, 1996, the National Heart, Lung, and Blood Institute sponsored a workshop in
Columbia, Md, entitled “The Medical and Cellular Implications of Myocardial Stunning …