Magnetic resonance imaging with hyperpolarized agents: methods and applications
In the past decade, hyperpolarized (HP) contrast agents have been under active
development for MRI applications to address the twin challenges of functional and …
development for MRI applications to address the twin challenges of functional and …
Fast imaging for hyperpolarized MR metabolic imaging
MRI with hyperpolarized carbon‐13 agents has created a new type of noninvasive, in vivo
metabolic imaging that can be applied in cell, animal, and human studies. The use of 13C …
metabolic imaging that can be applied in cell, animal, and human studies. The use of 13C …
Investigation of analysis methods for hyperpolarized 13C‐pyruvate metabolic MRI in prostate cancer patients
MRI using hyperpolarized (HP) carbon‐13 pyruvate is being investigated in clinical trials to
provide non‐invasive measurements of metabolism for cancer and cardiac imaging. In this …
provide non‐invasive measurements of metabolism for cancer and cardiac imaging. In this …
Translation of Carbon‐13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients
Purpose To develop and translate a metabolite‐specific imaging sequence using a
symmetric echo planar readout for clinical hyperpolarized (HP) Carbon‐13 (13C) …
symmetric echo planar readout for clinical hyperpolarized (HP) Carbon‐13 (13C) …
A variable resolution approach for improved acquisition of hyperpolarized 13C metabolic MRI
JW Gordon, AW Autry, S Tang… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To ameliorate tradeoffs between a fixed spatial resolution and signal‐to‐noise ratio
(SNR) for hyperpolarized 13C MRI. Methods In MRI, SNR is proportional to voxel volume but …
(SNR) for hyperpolarized 13C MRI. Methods In MRI, SNR is proportional to voxel volume but …
Kinetic modeling of hyperpolarized carbon-13 pyruvate metabolism in the human brain
Kinetic modeling of the in vivo pyruvate-to-lactate conversion is crucial to investigating
aberrant cancer metabolism that demonstrates Warburg effect modifications. Non-invasive …
aberrant cancer metabolism that demonstrates Warburg effect modifications. Non-invasive …
Hyperpolarized 13C MRI data acquisition and analysis in prostate and brain at University of California, San Francisco
Based on the expanding set of applications for hyperpolarized carbon‐13 (HP‐13C) MRI,
this work aims to communicate standardized methodology implemented at the University of …
this work aims to communicate standardized methodology implemented at the University of …
A regional bolus tracking and real‐time B1 calibration method for hyperpolarized 13C MRI
Purpose Acquisition timing and B1 calibration are two key factors that affect the quality and
accuracy of hyperpolarized 13C MRI. The goal of this project was to develop a new …
accuracy of hyperpolarized 13C MRI. The goal of this project was to develop a new …
A metabolite specific 3D stack-of-spirals bSSFP sequence for improved bicarbonate imaging in hyperpolarized [1-13C] Pyruvate MRI
X Liu, S Tang, D Cui, RA Bok, HY Chen… - Journal of Magnetic …, 2023 - Elsevier
Abstract 13 C-bicarbonate is a crucial measure of pyruvate oxidation and TCA cycle flux, but
is challenging to measure due to its relatively low concentration and thus will greatly benefit …
is challenging to measure due to its relatively low concentration and thus will greatly benefit …
[HTML][HTML] Acquisition strategies for spatially resolved magnetic resonance detection of hyperpolarized nuclei
GJ Topping, C Hundshammer, L Nagel… - … Resonance Materials in …, 2020 - Springer
Hyperpolarization is an emerging method in magnetic resonance imaging that allows
nuclear spin polarization of gases or liquids to be temporarily enhanced by up to five or six …
nuclear spin polarization of gases or liquids to be temporarily enhanced by up to five or six …