Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

The global emergence of multidrug-resistant Gram-negative bacteria is a growing threat to
antibiotic therapy. The chromosomally encoded drug efflux mechanisms that are ubiquitous …

Tetracyclines possess many properties considered ideal for antibiotic drugs, including
activity against Gram-positive and-negative pathogens, proven clinical safety, acceptable …

Dangerous, antibiotic resistant bacteria have been observed with increasing frequency over
the past several decades. In this review the factors that have been linked to this …

Serratia marcescens is a ubiquitous bacterium from order Enterobacterales displaying a
high genetic plasticity that allows it to adapt and persist in multiple niches including soil …

Serratia species, in particular Serratia marcescens, are significant human pathogens. S.
marcescens has a long and interesting taxonomic, medical experimentation, military …

Over the last 30 years, Serratia marcescens has become an important cause of nosocomial
infection. There have been many reports concerning the identification, antibiotic …

Tigecycline is unique glycylcycline class of semisynthetic antimicrobial agents developed for
the treatment of polymicrobial infections caused by multidrug-resistant Gram-positive and …

Tigecycline (TIG) exhibits broad-spectrum activity against many Gram-positive and Gram-
negative pathogens. However, clinical resistance has emerged recently and has been …

During the past decades, rates of multidrug-resistant (MDR) and carbapenem-resistant (CR)
Enterobacteriaceae clinical isolates, mainly Klebsiella spp., Escherichia coli, Enterobacter …