Helping koalas battle disease – Recent advances in Chlamydia and koala retrovirus (KoRV) disease understanding and treatment in koalas
BL Quigley, P Timms - FEMS Microbiology Reviews, 2020 - academic.oup.com
The iconic Australian marsupial, the koala (Phascolarctos cinereus), has suffered dramatic
population declines as a result of habitat loss and fragmentation, disease, vehicle collision …
population declines as a result of habitat loss and fragmentation, disease, vehicle collision …
Endogenous retroviruses drive resistance and promotion of exogenous retroviral homologs
ES Chiu, S VandeWoude - Annual Review of Animal …, 2021 - annualreviews.org
Endogenous retroviruses (ERVs) serve as markers of ancient viral infections and provide
invaluable insight into host and viral evolution. ERVs have been exapted to assist in …
invaluable insight into host and viral evolution. ERVs have been exapted to assist in …
The piRNA response to retroviral invasion of the koala genome
T Yu, BS Koppetsch, S Pagliarani, S Johnston… - Cell, 2019 - cell.com
Summary Antisense Piwi-interacting RNAs (piRNAs) guide silencing of established
transposons during germline development, and sense piRNAs drive ping-pong amplification …
transposons during germline development, and sense piRNAs drive ping-pong amplification …
Retroviral integrations contribute to elevated host cancer rates during germline invasion
Repeated retroviral infections of vertebrate germlines have made endogenous retroviruses
ubiquitous features of mammalian genomes. However, millions of years of evolution obscure …
ubiquitous features of mammalian genomes. However, millions of years of evolution obscure …
Koala retrovirus genetic diversity and transmission dynamics within captive koala populations
Koala populations are currently in rapid decline across Australia, with infectious diseases
being a contributing cause. The koala retrovirus (KoRV) is a gammaretrovirus present in …
being a contributing cause. The koala retrovirus (KoRV) is a gammaretrovirus present in …
Koala retrovirus genotyping analyses reveal a low prevalence of KoRV-A in Victorian koalas and an association with clinical disease
AR Legione, JLS Patterson… - Journal of medical …, 2017 - microbiologyresearch.org
Purpose. Koala retrovirus (KoRV) is undergoing endogenization into the genome of koalas
in Australia, providing an opportunity to assess the effect of retrovirus infection on the health …
in Australia, providing an opportunity to assess the effect of retrovirus infection on the health …
Molecular dynamics and mode of transmission of koala retrovirus as it invades and spreads through a wild Queensland koala population
BL Quigley, VA Ong, J Hanger, P Timms - Journal of Virology, 2018 - Am Soc Microbiol
The recent acquisition of a novel retrovirus (KoRV) by koalas (Phascolarctos cinereus) has
created new opportunities for retroviral research and new challenges for koala conservation …
created new opportunities for retroviral research and new challenges for koala conservation …
Koala immunogenetics and chlamydial strain type are more directly involved in chlamydial disease progression in koalas from two south east Queensland koala …
A Robbins, J Hanger, M Jelocnik, BL Quigley… - Scientific Reports, 2020 - nature.com
Chlamydial disease control is increasingly utilised as a management tool to stabilise
declining koala populations, and yet we have a limited understanding of the factors that …
declining koala populations, and yet we have a limited understanding of the factors that …
Envelope Recombination: A Major Driver in Shaping Retroviral Diversification and Evolution within the Host Genome
Endogenous retroviruses (ERVs) are integrated into host DNA as the result of ancient germ
line infections, primarily by extinct exogenous retroviruses. Thus, vertebrates' genomes …
line infections, primarily by extinct exogenous retroviruses. Thus, vertebrates' genomes …
Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype distributions
Koala retrovirus (KoRV) subtype A (KoRV-A) is currently in transition from exogenous virus
to endogenous viral element, providing an ideal system to elucidate retroviral–host …
to endogenous viral element, providing an ideal system to elucidate retroviral–host …