Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest
among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole …

Cancer is the second leading cause of death worldwide, and it results in around 9 million
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …

Coumarin and benzimidazole are privileged structures in medicinal chemistry and are
widely used in drug discovery and development due to their vast biological properties. The …

Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

Natural coumarins and their derivatives isolated from various plants or microorganisms have
inherent antioxidant, antibacterial, antifungal, antiviral and anticancer properties among …

Targeted therapy has emerged to be the cornerstone of advanced cancer treatment,
allowing for more selectivity and avoiding the common drug toxicity and resistance …

The outbreak of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has led to
coronavirus disease-19 (COVID-19); a pandemic disease that has resulted in devastating …

A small library of coumarin and their psoralen analogues EMAC10157a-bdg and
EMAC10160a-bdg has been designed and synthesised to investigate the effect of structural …

The VEGFR-2/AKT pathway is a crucial axis in tumor survival where it is highly dysregulated
in many cancer types. In this research, novel coumarin-acid hydrazides were synthesized …

The coumarin core (ie, 1-benzopyran-2 (2 H)-one) is a structural motif highly recurrent in
both natural products and bioactive molecules. Indeed, depending on the substituents and …