Astrocytes are abundant within mature neural circuits and are involved in brain disorders.
Here, we summarize our current understanding of astrocytes and Huntington's disease (HD) …

The physiological functions of astrocytes within neural circuits remain incompletely
understood. There has been progress in this regard from recent work on striatal astrocytes …

Glia, a non-excitable cell type once considered merely as the connective tissue between
neurons, is nowadays acknowledged for its essential contribution to multiple physiological …

Alteration of glutamatergic-neurotransmission is a hallmark of alcohol dependence. We
have previously reported that chronic ethanol-drinking downregulated glutamate transporter …

Huntington's disease (HD) is a neurodegenerative disorder, involving psychiatric, cognitive
and motor symptoms, caused by a CAG-repeat expansion encoding an extended …

Aims: Changes in glutamatergic transmission affect many aspects of neuroplasticity
associated with ethanol and drug addiction. For instance, ethanol-and drug-seeking …

Huntington's disease (HD) is a fatal, monogenic, autosomal dominant neurodegenerative
disease caused by a polyglutamine‐encoding CAG expansion in the huntingtin (HTT) gene …

Ceftriaxone is a beta-lactam antibiotic that increases the expression of the major glutamate
transporter, GLT-1. As such, ceftriaxone ameliorates symptoms across multiple rodent …

Dysregulation of glutamate homeostasis is a well-established core feature of
neuropsychiatric disorders. Extracellular glutamate concentration is regulated by glutamate …

The extracellular concentration of the two main neurotransmitters glutamate and GABA is
low but not negligible which enables a number of tonic actions. The effects of ambient GABA …