RFamide peptides as mediators in environmental control of GnRH neurons

I Parhar, S Ogawa, T Kitahashi - Progress in Neurobiology, 2012 - Elsevier
Hypothalamic gonadotropin-releasing hormone (GnRH) is a key hormone for reproductive
functions in vertebrates and non-vertebrates. Although GnRH neuronal system is regulated …

60 Years of POMC: melanocortin receptors: evolution of ligand selectivity for melanocortin peptides

RM Dores, L Liang, P Davis… - Journal of molecular …, 2016 - jme.bioscientifica.com
The evolution of the melanocortin receptors (MCRs) is linked to the evolution of
adrenocorticotrophic hormone (ACTH), the melanocyte-stimulating hormones (MSHs), and …

Hypothalamic inhibition of socio-sexual behaviour by increasing neuroestrogen synthesis

T Ubuka, S Haraguchi, Y Tobari, M Narihiro… - Nature …, 2014 - nature.com
Gonadotropin-inhibitory hormone (GnIH) is a hypothalamic neuropeptide that inhibits
gonadotropin secretion and socio-sexual behaviours. Oestrogen (neuroestrogen) …

A new pathway mediating social effects on the endocrine system: female presence acting via norepinephrine release stimulates gonadotropin-inhibitory hormone in …

Y Tobari, YL Son, T Ubuka, Y Hasegawa… - Journal of …, 2014 - Soc Neuroscience
Rapid effects of social interactions on transient changes in hormonal levels are known in a
wide variety of vertebrate taxa, ranging from fish to humans. Although these responses are …

Structure, function and evolution of GnIH

K Tsutsui, T Osugi, YL Son, T Ubuka - General and Comparative …, 2018 - Elsevier
Neuropeptides that possess the Arg-Phe-NH 2 motif at their C-termini (ie, RFamide
peptides) have been characterized in the nervous system of both invertebrates and …

The Arg–Phe‐amide peptide 26RFa/glutamine RF‐amide peptide and its receptor: IUPHAR Review 24

J Leprince, D Bagnol, R Bureau… - British journal of …, 2017 - Wiley Online Library
The RFamide neuropeptide 26RFa was first isolated from the brain of the European green
frog on the basis of cross‐reactivity with antibodies raised against bovine neuropeptide FF …

QRFP and its receptors regulate locomotor activity and sleep in zebrafish

A Chen, CN Chiu, EA Mosser, S Khan… - Journal of …, 2016 - Soc Neuroscience
The hypothalamus plays an important role in regulating sleep, but few hypothalamic sleep-
promoting signaling pathways have been identified. Here we demonstrate a role for the …

Oxytocin variation and brain region‐specific gene expression in a domesticated avian species

Y Tobari, C Theofanopoulou, C Mori… - Genes, Brain and …, 2022 - Wiley Online Library
The Bengalese finch was domesticated more than 250 years ago from the wild white‐
rumped munia (WRM). Similar to other domesticated species, Bengalese finches show a …

RFamide peptides in early vertebrate development

GK Sandvik, K Hodne, TM Haug, K Okubo… - Frontiers in …, 2014 - frontiersin.org
RFamides (RFa) are neuropeptides involved in many different physiological processes in
vertebrates, such as reproductive behavior, pubertal activation of the reproductive endocrine …

Hypothalamic QRFP: regulation of food intake and fat selection

SD Primeaux, MJ Barnes… - Hormone and Metabolic …, 2013 - thieme-connect.com
QRFP, a member of the RFamide-related peptide family, is a strongly conserved
hypothalamic neuropeptide that has been characterized in various species. Prepro-QRFP …