Altered neurovascular coupling as measured by optical imaging: a biomarker for Alzheimer's disease

K Kotliar, C Hauser, M Ortner, C Muggenthaler… - Scientific reports, 2017 - nature.com
Neurovascular coupling can be directly assessed by retinal vessel response to flickering
light using optical imaging methods. The response is altered in a number of ocular and …

Microvascular function and oxidative stress in adult individuals with early onset of cardiovascular disease

H Shokr, IHK Dias, D Gherghel - Scientific Reports, 2020 - nature.com
The current study aims to investigate retinal vascular function and its relationship with
systemic anti-oxidative defence capacity in normal individuals versus those with early …

Dynamic retinal vessel response to flicker in obesity: a methodological approach

KE Kotliar, IM Lanzl, A Schmidt-Trucksäss… - Microvascular …, 2011 - Elsevier
Obesity and related metabolic disorders affect vascular endothelial function. The use of the
Dynamic Vessel Analyzer (DVA) represents a modern methodological approach to analyze …

Altered retinal cerebral vessel oscillation frequencies in Alzheimer's disease compatible with impaired amyloid clearance

K Kotliar, M Ortner, A Conradi, P Hacker, C Hauser… - Neurobiology of …, 2022 - Elsevier
Retinal vessels are similar to cerebral vessels in their structure and function. Moderately low
oscillation frequencies of around 0.1 Hz have been reported as the driving force for …

Coexistence of macro‐and micro‐vascular abnormalities in newly diagnosed normal tension glaucoma patients

S Mroczkowska, A Ekart, V Sung, A Negi… - Acta …, 2012 - Wiley Online Library
Purpose: To investigate the coexistence of ocular microvascular and systemic
macrovascular abnormalities in early stage, newly diagnosed and previously untreated …

Assessing vascular function using dynamic retinal diameter measurements: a new insight on the endothelium

R Heitmar, RJ Summers - Thrombosis and haemostasis, 2012 - thieme-connect.com
Reliable assessment of endothelial function is important for the diagnosis, risk prediction
and treatment-monitoring in cardiovascular disease. Numerous techniques exist such as …

Non-invasive evaluation of neurovascular coupling in the murine retina by dynamic retinal vessel analysis

W Albanna, K Kotliar, JN Lüke, S Alpdogan, C Conzen… - PloS one, 2018 - journals.plos.org
Background Impairment of neurovascular coupling (NVC) was recently reported in the
context of subarachnoid hemorrhage and may correlate with disease severity and outcome …

Patients with early age-related macular degeneration exhibit signs of macro-and micro-vascular disease and abnormal blood glutathione levels

L Qin, SA Mroczkowska, A Ekart, SR Patel… - Graefe's Archive for …, 2014 - Springer
Background This pilot study aimed to investigate systemic and retinal vascular function and
their relationship to circulatory markers of cardiovascular risk in early age-related macular …

Novel non-contact retina camera for the rat and its application to dynamic retinal vessel analysis

D Link, C Strohmaier, BU Seifert, T Riemer… - Biomedical Optics …, 2011 - opg.optica.org
We present a novel non-invasive and non-contact system for reflex-free retinal imaging and
dynamic retinal vessel analysis in the rat. Theoretical analysis was performed prior to …

Measuring hyperemic response to light flicker stimulus using continuous laser speckle flowgraphy in mice

MR Tamplin, KA Broadhurst, AH Vitale… - Experimental eye …, 2022 - Elsevier
Alterations in neurovascular coupling have been associated with various ocular, cerebral,
and systemic vascular disorders. In the eye, changes in vessel caliber by dynamic vessel …