Background and aim Considering the amount of novel knowledge generated in the last five
years, a team of experienced hypertensionlogists was assembled to furnish updated clinical …

During the past decades, the mineralocorticoid receptor (MR) has evolved from a much‐
overlooked member of the steroid hormone receptor family to an important player, not only in …

Acute trauma stimulates local repair mechanisms but can also impact structures distant from
the injury, for example through the activity of circulating factors. To study the responses of …

Glucocorticoid hormones (GCs)—acting through hippocampal mineralocorticoid receptors
(MRs) and glucocorticoid receptors (GRs)—are critical to physiological regulation and …

The progesterone receptor (PR) mediates progesterone regulation of female reproductive
physiology, as well as gene transcription in non-reproductive tissues, such as brain, bone …

Primary aldosteronism, or Conn syndrome, is the most common endocrine cause of
hypertension. It is associated with a higher risk of cardiovascular, metabolic and renal …

Steroid receptors (SRs) are transcription factors activated by steroid hormones (SHs) that
belong to the nuclear receptors (NRs) superfamily. Several studies have shown that SRs are …

Stress and reproduction are both essential functions for vertebrate survival, ensuring on one
side adaptative responses to environmental changes and potential life threats, and on the …

Two randomised controlled trials have reported a reduction in mortality when adjunctive
hydrocortisone is administered in combination with fludrocortisone compared with placebo …

It is unknown whether and how osmoregulation is controlled by corticosteroid signaling in
the phylogenetically basal vertebrate group Agnatha, including lampreys and hagfishes. It is …