Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease
associated with memory and cognition impairment ultimately leading to death. It is the …

In a survey, from Brazilian books, we searched plants that are in popular use for purposes
resembling those of an adaptogen. This study focused on 24 books by authors from diverse …

Purpose The purpose of this study is to use a molecular docking approach to identify
potential estrogen mimics or anti-estrogens in phytochemicals found in popular dietary …

In Brazil, many plants are used as tonic, fortifier, aphrodisiac, anti-stress, among other uses
that are similar to the indications of an adaptogen. In general, such plants are used …

ETHNOPHARMACOLOGY RELEVANCE: Ptychopetalum olacoides Bentham
(PO)(Olacaceae), known as Marapuama, is regarded as a “nerve tonic” in the Amazon …

Although there are normal cognitive changes that take place as a person becomes older,
ageing in humans is generally associated with a deterioration of cognitive performance, in …

Maple syrup urine disease (MSUD) is an autosomal recessive metabolic disorder resulting
from deficiency of branched-chain α-keto acid dehydrogenase complex leading to branched …

Four new clerodane-type diterpenoids, ptychonolide (1), 20-O-methylptychonal acetal (2),
and an equilibrium mixture of ptychonal hemiacetal (3) and ptychonal (4), were isolated from …

From the MeOH extract of Ptychopetalum olacoides, which is used in Brazilian folk medicine
for the treatment of chronic degenerative conditions of the nervous system, four novel …

With the recognition that high levels of sustained stress are associated with the natural
course of countless illnesses, effective anti-stress agents have gained importance. Improved …