The glymphatic system: implications for drugs for central nervous system diseases
TJ Lohela, TO Lilius, M Nedergaard - Nature Reviews Drug Discovery, 2022 - nature.com
In the past decade, evidence for a fluid clearance pathway in the central nervous system
known as the glymphatic system has grown. According to the glymphatic system concept …
known as the glymphatic system has grown. According to the glymphatic system concept …
Non‐Cartesian parallel imaging reconstruction
KL Wright, JI Hamilton, MA Griswold… - Journal of Magnetic …, 2014 - Wiley Online Library
Non‐Cartesian parallel imaging has played an important role in reducing data acquisition
time in MRI. The use of non‐Cartesian trajectories can enable more efficient coverage of k …
time in MRI. The use of non‐Cartesian trajectories can enable more efficient coverage of k …
Ultra-fast magnetic resonance encephalography of physiological brain activity–glymphatic pulsation mechanisms?
V Kiviniemi, X Wang, V Korhonen… - Journal of Cerebral …, 2016 - journals.sagepub.com
The theory on the glymphatic convection mechanism of cerebrospinal fluid holds that
cardiac pulsations in part pump cerebrospinal fluid from the peri-arterial spaces through the …
cardiac pulsations in part pump cerebrospinal fluid from the peri-arterial spaces through the …
Human NREM sleep promotes brain-wide vasomotor and respiratory pulsations
H Helakari, V Korhonen, SC Holst… - Journal of …, 2022 - Soc Neuroscience
The physiological underpinnings of the necessity of sleep remain uncertain. Recent
evidence suggests that sleep increases the convection of cerebrospinal fluid (CSF) and …
evidence suggests that sleep increases the convection of cerebrospinal fluid (CSF) and …
Cardiovascular brain impulses in Alzheimer's disease
Accumulation of amyloid-β is a key neuropathological feature in brain of Alzheimer's disease
patients. Alterations in cerebral haemodynamics, such as arterial impulse propagation …
patients. Alterations in cerebral haemodynamics, such as arterial impulse propagation …
[HTML][HTML] Content-Free Awareness: EEG-fcMRI Correlates of Consciousness as Such in an Expert Meditator
U Winter, P LeVan, TL Borghardt, B Akin… - Frontiers in …, 2020 - frontiersin.org
The minimal neural correlate of the conscious state, regardless of the neural activity
correlated with the ever-changing contents of experience, has still not been identified …
correlated with the ever-changing contents of experience, has still not been identified …
[HTML][HTML] Sampling rate effects on resting state fMRI metrics
N Huotari, L Raitamaa, H Helakari, J Kananen… - Frontiers in …, 2019 - frontiersin.org
Low image sampling rates used in resting state functional magnetic resonance imaging (rs-
fMRI) may cause aliasing of the cardiorespiratory pulsations over the very low frequency …
fMRI) may cause aliasing of the cardiorespiratory pulsations over the very low frequency …
[HTML][HTML] The variability of functional MRI brain signal increases in Alzheimer's disease at cardiorespiratory frequencies
Biomarkers sensitive to prodromal or early pathophysiological changes in Alzheimer's
disease (AD) symptoms could improve disease detection and enable timely interventions …
disease (AD) symptoms could improve disease detection and enable timely interventions …
Real-time fMRI for brain-computer interfacing
Brain-computer interfaces (BCIs) based on functional magnetic resonance imaging (fMRI)
provide an important complement to other noninvasive BCIs. While fMRI has several …
provide an important complement to other noninvasive BCIs. While fMRI has several …
[HTML][HTML] Increased very low frequency pulsations and decreased cardiorespiratory pulsations suggest altered brain clearance in narcolepsy
Background Narcolepsy is a chronic neurological disease characterized by daytime sleep
attacks, cataplexy, and fragmented sleep. The disease is hypothesized to arise from …
attacks, cataplexy, and fragmented sleep. The disease is hypothesized to arise from …