An overview of ATP synthase, inhibitors, and their toxicity

AR Althaher, M Alwahsh - Heliyon, 2023 - cell.com
Mitochondrial complex V (ATP synthase) is a remarkable molecular motor crucial in
generating ATP and sustaining mitochondrial function. Its importance in cellular metabolism …

Toxicity of chemical-based hand sanitizers on children and the development of natural alternatives: a computational approach

T Mishra, S Vuppu - Critical Reviews in Toxicology, 2023 - Taylor & Francis
The unintended exposure of children to hand sanitizers poses a high risk of potentially fatal
complications. Skin irritation, dryness, cracking, peeling, hypoglycemia, apnea, and acidosis …

[HTML][HTML] Alternative Oxidase–Aid or obstacle to combat the rise of fungal pathogens?

ESM Edrich, L Duvenage, CW Gourlay - Biochimica et Biophysica Acta …, 2024 - Elsevier
Fungal pathogens present a growing threat to both humans and global health security alike.
Increasing evidence of antifungal resistance in fungal populations that infect both humans …

Automated profiling of gene function during embryonic development

RA Green, RN Khaliullin, Z Zhao, SD Ochoa… - Cell, 2024 - cell.com
Systematic functional profiling of the gene set that directs embryonic development is an
important challenge. To tackle this challenge, we used 4D imaging of C. elegans …

Cirsiliol and Quercetin Inhibit ATP Synthesis and Decrease the Energy Balance in Methicillin-Resistant Staphylococcus aureus (MRSA) and Methicillin-Resistant …

S Ravera, G Tancreda, L Vezzulli, AM Schito, I Panfoli - Molecules, 2023 - mdpi.com
Polyphenols have attracted attention in the fight against antibiotic-resistant bacteria, as they
show antibacterial action. Considering that polyphenols inhibit F1Fo-ATP synthase (ATP …

State-of-the-art strategies to prioritize Mycobacterium tuberculosis drug targets for drug discovery using a subtractive genomics approach

A Akinnuwesi, S Egieyeh, R Cloete - Frontiers in Drug Discovery, 2023 - frontiersin.org
Tuberculosis remains one of the causes of death from a single infectious bacterium. The
inappropriate use of antibiotics and patients' non-compliance among other factors drive the …

Insights into the potential dual-antibacterial mechanism of Kelisha capsule on Escherichia coli

G Shi, X Lu, Y Zheng, T Yang, E Zhu, Y Song… - … Medicine and Therapies, 2024 - Springer
Abstract Traditional Chinese medicine (TCM), AYURVEDA and Indian medicine are
essential in disease prevention and treatment. Kelisha capsule (KLSC), a TCM formula …

Cirsiliolo e Quercetina come inibitori della sintesi di ATP in ceppi di Staphylococcus meticillino-reistenti

F Pesce - 2023 - unire.unige.it
In questo lavoro ho valutato l'effetto di due flavonoidi, Cirsiliolo e Quercetina, sull'attività
dell'ATP sintasi batterica saggiata in tempo reale con Luminometria. Nota la loro azione …

Unlocking the Potential of Micromonospora sp.: Metabolomics and Molecular Modeling to Combat Antibiotic Resistance in Enteric Pathogens via ATP Synthase …

SA El-Shatoury, HK Megawer, MS Nafie, RR Makharita… - 2023 - researchsquare.com
Background The misuse of antibiotics in the last decade led to the quick emergence of
antibiotic resistance among pathogenic microorganisms. It has become a serious health …

An overview of ATP synthase, inhibitors, and their toxicity

AR Althaher, M Alwahsh - europepmc.org
Mitochondrial complex V (ATP synthase) is a remarkable molecular motor crucial in
generating ATP and sustaining mitochondrial function. Its importance in cellular metabolism …