Acquired hemophilia A: current guidance and experience from clinical practice
AM Pishko, BS Doshi - Journal of blood medicine, 2022 - Taylor & Francis
In acquired hemophilia A (AHA), autoantibodies to coagulation factor VIII (FVIII) neutralize
FVIII activity leading to a potentially severe bleeding diathesis that carries a high rate of …
FVIII activity leading to a potentially severe bleeding diathesis that carries a high rate of …
Off‐label use of emicizumab in persons with acquired haemophilia A and von Willebrand disease: a scoping review of the literature
VM Thomas, MY Abou‐Ismail, MY Lim - Haemophilia, 2022 - Wiley Online Library
Introduction Since the approval of emicizumab, a bispecific, factor VIII‐mimetic antibody, for
use in persons with congenital haemophilia A in 2018, there have been increasing case …
use in persons with congenital haemophilia A in 2018, there have been increasing case …
Emicizumab for the treatment of acquired hemophilia A
Acquired hemophilia A (AHA) is a severe bleeding disorder caused by inhibiting
autoantibodies to coagulation factor VIII (FVIII). For hemostatic treatment, bypassing agents …
autoantibodies to coagulation factor VIII (FVIII). For hemostatic treatment, bypassing agents …
[HTML][HTML] A prospective, multicenter, open-label phase III study of emicizumab prophylaxis in patients with acquired hemophilia A
M Shima, K Amano, Y Ogawa, K Yoneyama… - Journal of Thrombosis …, 2023 - Elsevier
Background Emicizumab is a bispecific antibody that mimics the cofactor function of
activated factor (F) VIII. It prevents bleeds in patients with congenital hemophilia A …
activated factor (F) VIII. It prevents bleeds in patients with congenital hemophilia A …
Emicizumab prophylaxis in patients with acquired haemophilia A (GTH-AHA-EMI): an open-label, single-arm, multicentre, phase 2 study
Background Acquired haemophilia A is caused by neutralising autoantibodies against
coagulation factor VIII, leading to severe bleeding. Standard treatment involves …
coagulation factor VIII, leading to severe bleeding. Standard treatment involves …
Single‐dose rituximab plus glucocorticoid versus cyclophosphamide plus glucocorticoid in patients with newly diagnosed acquired hemophilia A: A multicenter, open …
PJ Wang, R Zhou, F Xue, H Zhou, J Bai… - American Journal of …, 2024 - Wiley Online Library
Acquired hemophilia A (AHA) is a rare but serious bleeding disorder. Randomized
controlled trial (RCT) comparing the efficacy of immunosuppression therapy for AHA lacks …
controlled trial (RCT) comparing the efficacy of immunosuppression therapy for AHA lacks …
Management of acquired hemophilia A: results from the Spanish registry
ME Mingot-Castellano, J Pardos-Gea, S Haya… - Blood …, 2021 - ashpublications.org
Abstract The Spanish Acquired Hemophilia A (AHA) Registry is intended to update the
status of AHA in Spain. One hundred and fifty-four patients were included and …
status of AHA in Spain. One hundred and fifty-four patients were included and …
Combined immunosuppression for acquired hemophilia A: CyDRi is a highly effective low-toxicity regimen
B Simon, A Ceglédi, J Dolgos, P Farkas… - Blood, The Journal …, 2022 - ashpublications.org
Acquired hemophilia A (AHA) is a rare severe autoimmune bleeding disorder with significant
morbidity and mortality. Although critical for disease control, there is no consensus for the …
morbidity and mortality. Although critical for disease control, there is no consensus for the …
Pain management in hemophilia: expert recommendations
Introduction As a typical consequence of bleeding into muscles and joints, patients with
severe hemophilia suffer from acute and chronic pain. In spite of its high prevalence, pain in …
severe hemophilia suffer from acute and chronic pain. In spite of its high prevalence, pain in …
[HTML][HTML] Acquired haemophilia A: Italian Consensus Recommendations on diagnosis, general management and treatment of bleeding
A Coppola, M Franchini, A Tripodi, RC Santoro… - Blood …, 2022 - ncbi.nlm.nih.gov
Background Acquired haemophilia A (AHA) is a rare bleeding disorder due to
autoantibodies to coagulation factor VIII that may be secondary to autoimmune diseases …
autoantibodies to coagulation factor VIII that may be secondary to autoimmune diseases …