Tumor immune microenvironment lncRNAs
EG Park, SJ Pyo, Y Cui, SH Yoon… - Briefings in …, 2022 - academic.oup.com
Long non-coding ribonucleic acids (RNAs)(lncRNAs) are key players in tumorigenesis and
immune responses. The nature of their cell type-specific gene expression and other …
immune responses. The nature of their cell type-specific gene expression and other …
The how and why of lncRNA function: an innate immune perspective
EK Robinson, S Covarrubias, S Carpenter - Biochimica et Biophysica Acta …, 2020 - Elsevier
Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …
Epigenetic underpinnings of inflammation: Connecting the dots between pulmonary diseases, lung cancer and COVID-19
S Ahmad, S Manzoor, S Siddiqui, N Mariappan… - Seminars in cancer …, 2022 - Elsevier
Inflammation is an essential component of several respiratory diseases, such as chronic
obstructive pulmonary disease (COPD), asthma and acute respiratory distress syndrome …
obstructive pulmonary disease (COPD), asthma and acute respiratory distress syndrome …
The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2
T Vierbuchen, S Agarwal, JL Johnson… - Proceedings of the …, 2023 - National Acad Sciences
The nuclear long non-coding RNA LUCAT1 has previously been identified as a negative
feedback regulator of type I interferon and inflammatory cytokine expression in human …
feedback regulator of type I interferon and inflammatory cytokine expression in human …
Rapid 3D bioprinting of glioblastoma model mimicking native biophysical heterogeneity
Glioblastoma multiforme (GBM) is the most lethal primary brain tumor characterized by high
cellular and molecular heterogeneity, hypervascularization, and innate drug resistance …
cellular and molecular heterogeneity, hypervascularization, and innate drug resistance …
Long noncoding RNA HCP5 participates in premature ovarian insufficiency by transcriptionally regulating MSH5 and DNA damage repair via YB1
The genetic etiology of premature ovarian insufficiency (POI) has been well established to
date, however, the role of long noncoding RNAs (lncRNAs) in POI is largely unknown. In this …
date, however, the role of long noncoding RNAs (lncRNAs) in POI is largely unknown. In this …
[HTML][HTML] Exosomal long non-coding RNAs: emerging players in the tumor microenvironment
AS Pathania, KB Challagundla - Molecular Therapy-Nucleic Acids, 2021 - cell.com
Recent advances in exosome biology have uncovered a significant role of exosomes in
cancer and make them a determining factor in intercellular communication. Exosomes are …
cancer and make them a determining factor in intercellular communication. Exosomes are …
[HTML][HTML] The Role of microRNAs and Long Non-Coding RNAs in the Regulation of the Immune Response to Mycobacterium tuberculosis Infection
M Kundu, J Basu - Frontiers in immunology, 2021 - frontiersin.org
Non-coding RNAs have emerged as critical regulators of the immune response to infection.
MicroRNAs (miRNAs) are small non-coding RNAs which regulate host defense mechanisms …
MicroRNAs (miRNAs) are small non-coding RNAs which regulate host defense mechanisms …
The role of lncRNAs in innate immunity and inflammation
K Walther, LN Schulte - RNA biology, 2021 - Taylor & Francis
The innate immune system relies on a germ-line-encoded repertoire of pattern recognition
receptors (PRRs), activated by deeply conserved pathogen signatures, such as bacterial cell …
receptors (PRRs), activated by deeply conserved pathogen signatures, such as bacterial cell …
A primer on cytokines
Cytokines are pleiotropic polypeptides that control the development of and responses
mediated by immune cells. Cytokine classification predominantly relies on [1] the target …
mediated by immune cells. Cytokine classification predominantly relies on [1] the target …