Prostate cancer is a highly prevalent form of cancer that is usually slow-developing and
benign. Due to its high prevalence, it is, however, still the second most common cause of …

Prostate cancer (PC) is the most prevalent male urogenital cancer worldwide. PC patients
presenting an advanced or metastatic cancer succumb to the disease, even after therapeutic …

PKCε, an oncogenic member of the PKC family, is aberrantly overexpressed in epithelial
cancers. To date, little is known about functional interactions of PKCε with other genetic …

The pro-oncogenic kinase PKCε is overexpressed in human prostate cancer and cooperates
with loss of the tumor suppressor Pten for the development of prostatic adenocarcinoma …

Parkinson's disease (PD) is second only to Alzheimer's disease as the most common
devastating human neurodegenerative disorder. Despite intense investigation, no curative …

Looking to the sustained psoriatic arthritis (PsA) joint as a model of local human
inflammation, this study was designed to assess the T lymphocyte signal transduction …

Protein kinase C (PKC) is a multifunctional family of Ser-Thr kinases widely implicated in the
regulation of fundamental cellular functions, including proliferation, polarity, motility, and …

The bone is a preferred site for metastatic homing of prostate cancer cells. Once prostate
cancer patients develop skeletal metastases, they eventually succumb to the disease; …

Despite our extensive knowledge on the biology of protein kinase C (PKC) and its
involvement in disease, limited success has been attained in the generation of PKC isozyme …

Aspergillus fumigatus is an environmental fungus that can cause life-threatening pulmonary
disease. Infections initiate when conidia are inhaled and land deep inside the small airways …