Mechanistic model of nutrient uptake explains dichotomy between marine oligotrophic and copiotrophic bacteria
Marine bacterial diversity is immense and believed to be driven in part by trade-offs in
metabolic strategies. Here we consider heterotrophs that rely on organic carbon as an …
metabolic strategies. Here we consider heterotrophs that rely on organic carbon as an …
Integrating gene expression data into a genome-scale metabolic model to identify reprogramming during adaptive evolution
S Yazdanpanah, E Motamedian, SA Shojaosadati - PloS one, 2023 - journals.plos.org
The development of a method for identifying latent reprogramming in gene expression data
resulting from adaptive laboratory evolution (ALE) in response to genetic or environmental …
resulting from adaptive laboratory evolution (ALE) in response to genetic or environmental …
Understanding and mathematical modelling of cellular resource allocation in microorganisms: a comparative synthesis
Background The rising consensus that the cell can dynamically allocate its resources
provides an interesting angle for discovering the governing principles of cell growth and …
provides an interesting angle for discovering the governing principles of cell growth and …
Metabolic excretion associated with nutrient–growth dysregulation promotes the rapid evolution of an overt metabolic defect
In eukaryotes, conserved mechanisms ensure that cell growth is coordinated with nutrient
availability. Overactive growth during nutrient limitation (“nutrient–growth dysregulation”) can …
availability. Overactive growth during nutrient limitation (“nutrient–growth dysregulation”) can …
Understanding the impact of the cofactor swapping of isocitrate dehydrogenase over the growth phenotype of Escherichia coli on acetate by using constraint-based …
It has been proposed that NADP+-specificity of isocitrate dehydrogenase (ICDH) evolved as
an adaptation of microorganisms to grow on acetate as the sole source of carbon and …
an adaptation of microorganisms to grow on acetate as the sole source of carbon and …