The WD40 domain is one of the most abundant and interacting domains in the eukaryotic
genome. In proteins the WD domain folds into a β-propeller structure, providing a platform …

Sperm motility is necessary for the transport of male DNA to eggs in species with both
external and internal fertilization. Flagella comprise several proteins for generating and …

Dr. Harris has played a major role in the development of this organism as a model system.
Her previous version of the Chlamydomonas Sourcebook which published in 1989, has …

The working mechanism of the eukaryotic flagellar axoneme remains one of nature's most
enduring puzzles. The basic mechanical operation of the axoneme is now a story that is …

Motile cilia are essential components of the mucociliary escalator and are central to
respiratory-tract host defenses. Abnormalities in these evolutionarily conserved organelles …

Dyneins are large minus‐end‐directed microtubule motors. Each dynein contains at least
one dynein heavy chain (DHC) and a variable number of intermediate chains (IC), light …

Ciliary motility is crucial for the development and health of many organisms. Motility depends
on the coordinated activity of multiple dynein motors arranged in a precise pattern on the …

Intraflagellar transport (IFT), which is the bidirectional movement of particles within flagella,
is required for flagellar assembly. IFT particles are composed of∼ 16 proteins, which are …

The WD-repeat-containing proteins form a very large family that is diverse in both its function
and domain structure. Within all these proteins the WD-repeat domains are thought to have …

Cilia/flagella are conserved organelles that generate fluid flow in eukaryotes. The bending
motion of flagella requires concerted activity of dynein motors. Although it has been reported …