[HTML][HTML] Ayurvedic and other herbal remedies for dengue: an update
Dengue fever is a flu-like ailment propagated by female mosquitos of the Aedes aegypti
species. It is also known as dandaka jwara in Ayurveda. It is most common in the world's …
species. It is also known as dandaka jwara in Ayurveda. It is most common in the world's …
Antiviral phytochemicals as potent inhibitors against NS3 protease of dengue virus
Dengue, a mosquito-borne disease, has appeared as a major infectious disease globally.
The virus requires its proteins to replicate and reproduce in the host cell. The NS3 protease …
The virus requires its proteins to replicate and reproduce in the host cell. The NS3 protease …
The SARS-CoV-2 Mpro Dimer-Based Screening System: A Synthetic Biology Tool for Identifying Compounds with Dimerization Inhibitory Potential
EA Giri-Rachman, VV Effendy, MHS Azmi… - ACS Synthetic …, 2024 - ACS Publications
The COVID-19 endemic remains a global concern. The search for effective antiviral
candidates is still needed to reduce disease risk. However, the availability of high biosafety …
candidates is still needed to reduce disease risk. However, the availability of high biosafety …
Porphyrin-derived carbon dots for an enhanced antiviral activity targeting the CTD of SARS-CoV-2 nucleocapsid
A Fibriani, AAP Taharuddin, N Yamahoki… - Journal of Genetic …, 2023 - Springer
Background Since effective antiviral drugs for COVID-19 are still limited in number, the
exploration of compounds that have antiviral activity against SARS-CoV-2 is in high …
exploration of compounds that have antiviral activity against SARS-CoV-2 is in high …
Arylamide as potential selective inhibitor for matrix metalloproteinase 9 (MMP9): design, synthesis, biological evaluation, and molecular modeling
Previous studies have reported that compounds bearing an arylamide linked to a
heterocyclic planar ring have successfully inhibited the hemopexin-like domain (PEX9) of …
heterocyclic planar ring have successfully inhibited the hemopexin-like domain (PEX9) of …
Synthesis and biological activity of imidazole phenazine derivatives as potential inhibitors for NS2B-NS3 dengue protease
A series of new imidazole-phenazine derivatives were synthesized via a two-step process.
The condensation of 2, 3-diaminophenazine and benzaldehyde derivatives proceeds with …
The condensation of 2, 3-diaminophenazine and benzaldehyde derivatives proceeds with …
Next Generation of Fluorometric Protease Assays: 7‐Nitrobenz‐2‐oxa‐1, 3‐diazol‐4‐yl‐amides (NBD‐Amides) as Class‐Spanning Protease Substrates
H Maus, P Müller, M Meta, SN Hoba… - … A European Journal, 2023 - Wiley Online Library
Fluorometric assays are one of the most frequently used methods in medicinal chemistry.
Over the last 50 years, the reporter molecules for the detection of protease activity have …
Over the last 50 years, the reporter molecules for the detection of protease activity have …
Diversity of medicinal plants used in the treatment and management of viral diseases transmitted by mosquitoes in the tropics
Mosquitoes are insects with slender bodies, three pairs of jointed legs, a pair of wings, and
an elongated mouthpart for sucking the blood of vertebrate animals including humans. The …
an elongated mouthpart for sucking the blood of vertebrate animals including humans. The …
Anti-cholinesterase activity of chalcone derivatives: synthesis, in vitro assay and molecular docking study
Background: Chalcones, originated from natural product, have been broadly studied their
biological activity against various proteins which at the molecular level, are responsible for …
biological activity against various proteins which at the molecular level, are responsible for …
Computational study of nitro-benzylidene phenazine as dengue virus-2 NS2B-NS3 protease inhibitor
According to the World Health Organisation (WHO), as of week 23 of 2022, there were more
than 1,311 cases of dengue in Malaysia, with 13 deaths reported. Furthermore, there was an …
than 1,311 cases of dengue in Malaysia, with 13 deaths reported. Furthermore, there was an …