RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET
J Seflova, JA Schwarz, AN Smith… - ACS Chemical …, 2023 - ACS Publications
Hyperactivity of cardiac sarcoplasmic reticulum (SR) ryanodine receptor (RyR2) Ca2+-
release channels contributes to heart failure and arrhythmias. Reducing the RyR2 activity …
release channels contributes to heart failure and arrhythmias. Reducing the RyR2 activity …
The Effect of Acidic Residues on the Binding between Opicalcin1 and Ryanodine Receptor from the Structure–Functional Analysis
J Yao, X Hua, W Huo, L Xiao, Y Wang… - Journal of Natural …, 2023 - ACS Publications
Calcin is a group ligand with high affinity and specificity for the ryanodine receptors (RyRs).
Little is known about the effect of its acidic residues on the spacial structure as well as the …
Little is known about the effect of its acidic residues on the spacial structure as well as the …
Comparison of the structure-function of five newly members of the calcin family
X Hua, J Yao, X Liu, Q Liu, Y Deng, S Li… - International Journal of …, 2024 - Elsevier
Calcins are a group of scorpion toxin peptides specifically binding to ryanodine receptors
(RyRs) with high affinity, and have the ability to activate and stabilize RyR in a long-lasting …
(RyRs) with high affinity, and have the ability to activate and stabilize RyR in a long-lasting …
[HTML][HTML] OpiCa1-PEG-PLGA nanomicelles antagonize acute heart failure induced by the cocktail of epinephrine and caffeine
J Li, F Wang, X Liu, Z Yang, X Hua, H Zhu… - Materials Today Bio, 2023 - Elsevier
Abstract Background Reducing Ca 2+ content in the sarcoplasmic reticulum (SR) through
ryanodine receptors (RyRs) by calcin is a potential intervention strategy for the SR Ca 2+ …
ryanodine receptors (RyRs) by calcin is a potential intervention strategy for the SR Ca 2+ …
Localising elements in single-particle reconstructions by REEL-EM: Reconstructed Electron Energy-Loss-Elemental Mapping
For structures determined by single particle cryo-EM, no technique currently exists for
mapping elements to defined locations, leading to errors in the assignment of metals and …
mapping elements to defined locations, leading to errors in the assignment of metals and …