Creatine biosynthesis and transport in health and disease

MJC Curt, PM Voicu, M Fontaine, AF Dessein… - Biochimie, 2015 - Elsevier
Creatine is physiologically provided equally by diet and by endogenous synthesis from
arginine and glycine with successive involvements of arginine glycine amidinotransferase …

Creatine supplementation, physical exercise and oxidative stress markers: a review of the mechanisms and effectiveness

H Arazi, E Eghbali, K Suzuki - Nutrients, 2021 - mdpi.com
Oxidative stress is the result of an imbalance between the generation of reactive oxygen
species (ROS) and their elimination by antioxidant mechanisms. ROS degrade biogenic …

[HTML][HTML] The effect of eight weeks resistance and endurance training on some angiogenesis factors of hippocampus tissue in male wistar rats

M Sadegh Ghomi, M Kashef… - Journal of Sport and …, 2021 - joeppa.sbu.ac.ir
Purpose: One of the cause of adaptations due to exercise training is increased capillary
density or angiogenesis. increased blood flow to hippocampus tissue causes improvement …

Cell rearrangement and oxidant/antioxidant imbalance in Huntington's disease

F D'Egidio, V Castelli, A Cimini, M d'Angelo - Antioxidants, 2023 - mdpi.com
Huntington's Disease (HD) is a hereditary neurodegenerative disorder caused by the
expansion of a CAG triplet repeat in the HTT gene, resulting in the production of an aberrant …

[HTML][HTML] A review of creatine supplementation in age-related diseases: more than a supplement for athletes

RN Smith, AS Agharkar, EB Gonzales - F1000Research, 2014 - ncbi.nlm.nih.gov
Creatine is an endogenous compound synthesized from arginine, glycine and methionine.
This dietary supplement can be acquired from food sources such as meat and fish, along …

Creatine and the liver: metabolism and possible interactions

RP Barcelos, ST Stefanello, JL Mauriz… - Mini reviews in …, 2016 - ingentaconnect.com
The process of creatine synthesis occurs in two steps, catalyzed by L-arginine: glycine
amidinotransferase (AGAT) and guanidinoacetate N-methyltransferase (GAMT), which take …

Creatine Supplementation to Improve Sarcopenia in Chronic Liver Disease: Facts and Perspectives

R Casciola, L Leoni, B Cuffari, M Pecchini, R Menozzi… - Nutrients, 2023 - mdpi.com
Creatine supplementation has been one of the most studied and useful ergogenic nutritional
support for athletes to improve performance, strength, and muscular mass. Over time …

Creatine as a neuroprotector: an actor that can play many parts

EP Marques, ATS Wyse - Neurotoxicity Research, 2019 - Springer
Creatine is a nitrogenous organic acid that plays a central role as an energy buffer in high
energy demanding systems, including the muscular and the central nervous system. It can …

Protective effects of antioxidants in Huntington's disease: an extensive review

MM Essa, M Moghadas, T Ba-Omar… - Neurotoxicity …, 2019 - Springer
Huntington's disease (HD) is a hereditary neurodegenerative disease of the central nervous
system (CNS). Onset of HD occurs between the ages of 30 and 50 years, although few …

Resistance training and L-arginine supplementation are determinant in genomic stability, cardiac contractility and muscle mass development in rats

GP Stefani, B Marmett, JP Alves, GB Möller, TG Heck… - PLoS …, 2018 - journals.plos.org
L-arginine supplementation has been related to increased maximum strength and
improvement of hemodynamic parameters in several diseases. The aim of our study was to …