A Comprehensive Review on the Therapeutic Potential of Curcuma longa Linn. in Relation to its Major Active Constituent Curcumin

S Fuloria, J Mehta, A Chandel, M Sekar… - Frontiers in …, 2022 - frontiersin.org
Curcuma longa Linn.(C. longa), popularly known as turmeric, belongs to the Zingiberaceae
family and has a long historical background of having healing properties against many …

Curcumin formulations for better bioavailability: what we learned from clinical trials thus far?

M Hegde, S Girisa, B BharathwajChetty, R Vishwa… - ACS …, 2023 - ACS Publications
Curcumin has been credited with a wide spectrum of pharmacological properties for the
prevention and treatment of several chronic diseases such as arthritis, autoimmune …

Nanocurcumin: A promising candidate for therapeutic applications

A Karthikeyan, N Senthil, T Min - Frontiers in Pharmacology, 2020 - frontiersin.org
Curcuma longa is an important medicinal plant and a spice in Asia. Curcumin
(diferuloylmethane) is a hydrophobic bioactive ingredient found in a rhizome of the C. longa …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Curcumin-loaded nanoparticles: A novel therapeutic strategy in treatment of central nervous system disorders

H Yavarpour-Bali, M Ghasemi-Kasman… - International journal of …, 2019 - Taylor & Francis
Curcumin as a hydrophobic polyphenol is extracted from the rhizome of Curcuma longa.
Curcumin is widely used as a dietary spice and a topical medication for the treatment of …

Oxidative stress in amyotrophic lateral sclerosis: pathophysiology and opportunities for pharmacological intervention

T Cunha-Oliveira, L Montezinho… - Oxidative medicine …, 2020 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease or Charcot
disease, is a fatal neurodegenerative disease that affects motor neurons (MNs) and leads to …

Curcumin-based nanoformulations: A promising adjuvant towards cancer treatment

S Hafez Ghoran, A Calcaterra, M Abbasi, F Taktaz… - Molecules, 2022 - mdpi.com
Throughout the United States, cancer remains the second leading cause of death.
Traditional treatments induce significant medical toxic effects and unpleasant adverse …

The effects of curcumin intake on wound healing and metabolic status in patients with diabetic foot ulcer: A randomized, double‐blind, placebo‐controlled trial

M Mokhtari, R Razzaghi… - Phytotherapy …, 2021 - Wiley Online Library
This study was conducted to determine the effects of curcumin intake on wound healing and
metabolic status in patients with diabetic foot ulcer (DFU). The current randomized, double …

Natural antioxidant compounds as potential pharmaceutical tools against neurodegenerative diseases

A Marino, M Battaglini, N Moles, G Ciofani - ACS omega, 2022 - ACS Publications
Natural antioxidants are a very large diversified family of molecules classified by activity
(enzymatic or nonenzymatic), chemical-physical properties (eg, hydrophilic or lipophilic) …

Antioxidant therapy in oxidative stress-induced neurodegenerative diseases: Role of nanoparticle-based drug delivery systems in clinical translation

A Ashok, SS Andrabi, S Mansoor, Y Kuang, BK Kwon… - Antioxidants, 2022 - mdpi.com
Free radicals are formed as a part of normal metabolic activities but are neutralized by the
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …