Liver ischaemia–reperfusion injury: a new understanding of the role of innate immunity

H Hirao, K Nakamura… - … reviews Gastroenterology & …, 2022 - nature.com
Liver ischaemia–reperfusion injury (LIRI), a local sterile inflammatory response driven by
innate immunity, is one of the primary causes of early organ dysfunction and failure after …

Cellular mechanisms of liver fibrosis

P Acharya, K Chouhan, S Weiskirchen… - Frontiers in …, 2021 - frontiersin.org
The liver is a central organ in the human body, coordinating several key metabolic roles. The
structure of the liver which consists of the distinctive arrangement of hepatocytes, hepatic …

Exercise plasma boosts memory and dampens brain inflammation via clusterin

Z De Miguel, N Khoury, MJ Betley, B Lehallier… - Nature, 2021 - nature.com
Physical exercise is generally beneficial to all aspects of human and animal health, slowing
cognitive ageing and neurodegeneration. The cognitive benefits of physical exercise are …

Covid‐19 and dengue: double punches for dengue‐endemic countries in Asia

H Harapan, M Ryan, B Yohan… - Reviews in medical …, 2021 - Wiley Online Library
Summary The coronavirus disease 2019 (Covid‐19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is an international public health crisis …

An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson's disease participants

DA Hall, RM Voigt, TM Cantu-Jungles… - Nature …, 2023 - nature.com
A pro-inflammatory intestinal microbiome is characteristic of Parkinson's disease (PD).
Prebiotic fibers change the microbiome and this study sought to understand the utility of …

Oxidative stress is a key modulator in the development of nonalcoholic fatty liver disease

Y Ma, G Lee, SY Heo, YS Roh - Antioxidants, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, and scientific studies consistently report that NAFLD development can be …

Lipid nanoparticle technology for therapeutic gene regulation in the liver

D Witzigmann, JA Kulkarni, J Leung, S Chen… - Advanced drug delivery …, 2020 - Elsevier
Hereditary genetic disorders, cancer, and infectious diseases of the liver affect millions of
people around the globe and are a major public health burden. Most contemporary …

Liver immunology and its role in inflammation and homeostasis

MW Robinson, C Harmon, C O'Farrelly - Cellular & molecular …, 2016 - nature.com
The human liver is usually perceived as a non-immunological organ engaged primarily in
metabolic, nutrient storage and detoxification activities. However, we now know that the …

Oxidative stress in liver pathophysiology and disease

A Allameh, R Niayesh-Mehr, A Aliarab, G Sebastiani… - Antioxidants, 2023 - mdpi.com
The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Inflammatory pathways in alcoholic steatohepatitis

B Gao, MF Ahmad, LE Nagy, H Tsukamoto - Journal of hepatology, 2019 - Elsevier
Inflammatory processes are primary contributors to the development and progression of
alcoholic steatohepatitis (ASH), with severe alcoholic hepatitis characterised by non …