[HTML][HTML] Anisotropic scaffolds for peripheral nerve and spinal cord regeneration

W Xue, W Shi, Y Kong, M Kuss, B Duan - Bioactive materials, 2021 - Elsevier
The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …

Peripheral nerve injury: current challenges, conventional treatment approaches, and new trends in biomaterials-based regenerative strategies

R López-Cebral, J Silva-Correia, RL Reis… - ACS Biomaterials …, 2017 - ACS Publications
Damage to peripheral nerves is a widely extended health problem, causing important
socioeconomic costs worldwide. Indeed, peripheral nerve injuries (PNI) have been …

Aligned PCL fiber conduits immobilized with nerve growth factor gradients enhance and direct sciatic nerve regeneration

L Zhu, S Jia, T Liu, L Yan, D Huang… - Advanced functional …, 2020 - Wiley Online Library
Topographical guidance and chemotaxis are crucial factors for peripheral nerve
regeneration. This study describes the preparation of highly aligned poly (ε …

Sema3A secreted by sensory nerve induces bone formation under mechanical loads

H Mei, Z Li, Q Lv, X Li, Y Wu, Q Feng, Z Jiang… - International Journal of …, 2024 - nature.com
Bone formation and deposition are initiated by sensory nerve infiltration in adaptive bone
remodeling. Here, we focused on the role of Semaphorin 3A (Sema3A), expressed by …

Surface patterning of hydrogel biomaterials to probe and direct cell–matrix interactions

BG Munoz‐Robles, I Kopyeva… - Advanced Materials …, 2020 - Wiley Online Library
Due to their mechanical and structural similarity to native tissues, hydrogel biomaterials
have gained tremendous popularity for applications in 3D tissue culture, therapeutic …

Regeneration of the peripheral nerve via multifunctional electrospun scaffolds

N Ghane, S Khalili, S Nouri Khorasani… - … Research Part A, 2021 - Wiley Online Library
Over the last two decades, electrospun scaffolds have proved to be advantageous in the
field of nerve tissue regeneration by connecting the cavity among the proximal and distal …

[HTML][HTML] Functionalization strategies of electrospun nanofibrous scaffolds for nerve tissue engineering

J Qian, Z Lin, Y Liu, Z Wang, Y Lin, C Gong… - Smart Materials in …, 2021 - Elsevier
Despite the high number of nerve injuries, there is a lack of an effective nerve repair strategy
to restore nerve function. As crucial candidates for tissue engineering, electrospun …

The efficacy of graphene foams for culturing mesenchymal stem cells and their differentiation into dopaminergic neurons

N Tasnim, V Thakur, M Chattopadhyay… - Stem Cells …, 2018 - Wiley Online Library
The implantation of stem cells in vivo is the ideal approach for the restoration of normal life
functions, such as replenishing the decreasing levels of affected dopaminergic (DA) neurons …

Integrative utilization of microenvironments, biomaterials and computational techniques for advanced tissue engineering

A Shamloo, N Mohammadaliha, M Mohseni - Journal of biotechnology, 2015 - Elsevier
This review aims to propose the integrative implementation of microfluidic devices,
biomaterials, and computational methods that can lead to a significant progress in tissue …

Electrospun collagen fibers with spatial patterning of SDF1α for the guidance of neural stem cells

X Li, H Liang, J Sun, Y Zhuang, B Xu… - Advanced healthcare …, 2015 - Wiley Online Library
Producing gradients of biological cues into nerve conduits is crucial for nerve guidance and
regeneration. Herein, the fabrication of gradients of stromal cell‐derived factor‐1α (SDF1α) …