ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

[HTML][HTML] Nonprostatic diseases on PSMA PET imaging: a spectrum of benign and malignant findings

F de Galiza Barbosa, MA Queiroz, RF Nunes, LB Costa… - Cancer Imaging, 2020 - Springer
PSMA PET imaging was originally used to assess biochemical recurrence of prostate cancer
(PCa), but its clinical use was promptly extended to detection, staging and therapy response …

A perspective on the evolving story of PSMA biology, PSMA-based imaging, and endoradiotherapeutic strategies

DS O'Keefe, DJ Bacich, SS Huang… - Journal of Nuclear …, 2018 - Soc Nuclear Med
In this review, we cover the evolution of knowledge on the biology of prostate-specific
membrane antigen (PSMA) and its translation to therapy. The usual key to discovery is a …

Investigating PSMA-targeted radioligand therapy efficacy as a function of cellular PSMA levels and intratumoral PSMA heterogeneity

K Current, C Meyer, CE Magyar, CE Mona… - Clinical Cancer …, 2020 - AACR
Purpose: Prostate-specific membrane antigen (PSMA) targeting radioligands deliver
radiation to PSMA-expressing cells. However, the relationship between PSMA levels and …

Prostate-specific membrane antigen PET in prostate cancer

C Lawhn-Heath, A Salavati, SC Behr, SP Rowe… - Radiology, 2021 - pubs.rsna.org
Prostate-specific membrane antigen (PSMA)–targeted radiopharmaceuticals are playing a
large role at the time of initial staging and biochemical recurrence for localizing prostate …

Nuclear medicine and molecular imaging advances in the 21st century

SC Vaz, F Oliveira, K Herrmann… - The British journal of …, 2020 - academic.oup.com
Currently, Nuclear Medicine has a clearly defined role in clinical practice due to its
usefulness in many medical disciplines. It provides relevant diagnostic and therapeutic …

Prostate-specific membrane antigen (PSMA)-targeted PET imaging of prostate cancer: an update on important pitfalls

S Sheikhbahaei, RA Werner, LB Solnes… - Seminars in nuclear …, 2019 - Elsevier
The continuing adoption of prostate specific membrane antigen (PSMA)-targeted PET for
prostate cancer molecular imaging requires imagers and clinicians alike to be aware of the …

[HTML][HTML] PSMA expression in solid tumors beyond the prostate gland: ready for theranostic applications?

C Lauri, L Chiurchioni, VM Russo, L Zannini… - Journal of Clinical …, 2022 - mdpi.com
In the past decades, the expanding use of prostate-specific membrane antigen (PSMA)
imaging for prostate cancer has led to the incidental detection of a lot of extra-prostatic …

Comprehensive evaluation of 68Ga-PSMA-11 PET/CT parameters for discriminating pathological characteristics in primary clear-cell renal cell carcinoma

J Gao, Q Xu, Y Fu, K He, C Zhang, Q Zhang… - European Journal of …, 2021 - Springer
Purpose To evaluate parameters derived from 68 Ga-PSMA-11 PET/CT images for
discriminating pathological characteristics in primary clear-cell renal cell carcinoma …

Theranostics: leveraging molecular imaging and therapy to impact patient management and secure the future of nuclear medicine

LB Solnes, RA Werner, KM Jones… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Nuclear medicine is experiencing a renaissance, with US Food and Drug Administration
approval recently being obtained for theranostic agents and a wide variety of such agents …