Citrulline, biomarker of enterocyte functional mass and dietary supplement. Metabolism, transport, and current evidence for clinical use

S Maric, T Restin, JL Muff, SM Camargo… - Nutrients, 2021 - mdpi.com
L-Citrulline is a non-essential but still important amino acid that is released from enterocytes.
Because plasma levels are reduced in case of impaired intestinal function, it has become a …

Prevotella copri and microbiota members mediate the beneficial effects of a therapeutic food for malnutrition

HW Chang, EM Lee, Y Wang, C Zhou, KM Pruss… - Nature …, 2024 - nature.com
Microbiota-directed complementary food (MDCF) formulations have been designed to repair
the gut communities of malnourished children. A randomized controlled trial demonstrated …

[HTML][HTML] Correlates of plasma citrulline, a potential marker of enterocyte mass, among children with stunting: a cross-sectional study in Uganda

H Pesu, J Mbabazi, R Mutumba, O Savolainen… - The Journal of …, 2024 - Elsevier
Background Environmental enteric dysfunction (EED) is associated with stunting. Citrulline,
produced in mature enterocytes, may be a valuable biomarker of small intestinal enterocyte …

Infections and nutrient deficiencies during infancy predict impaired growth at 5 years: Findings from the MAL-ED study in Pakistan

D González-Fernández, S Cousens, A Rizvi… - Frontiers in …, 2023 - frontiersin.org
Background Socio-economic, nutritional, and infectious factors have been associated with
impaired infant growth, but how the presence of these factors during infancy affects growth …

Serum cobalamin in children with moderate acute malnutrition in Burkina Faso: Secondary analysis of a randomized trial

H Friis, B Cichon, C Fabiansen, AS Iuel-Brockdorff… - PLoS …, 2022 - journals.plos.org
Background Among children with moderate acute malnutrition (MAM) the level of serum
cobalamin (SC) and effect of food supplements are unknown. We aimed to assess …

[HTML][HTML] Prevotella copri-related effects of a therapeutic food for malnutrition

HW Chang, EM Lee, Y Wang, C Zhou, KM Pruss… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Preclinical and clinical studies are providing evidence that the healthy growth of infants and
children reflects, in part, healthy development of their gut microbiomes 1-5. This process of …

Citrulline and kynurenine to tryptophan ratio: potential EED (environmental enteric dysfunction) biomarkers in acute watery diarrhea among children in Bangladesh

R Das, MA Haque, RA Sobi, AA Sultana, MA Khan… - Scientific Reports, 2023 - nature.com
Two emerging biomarkers of environmental enteric dysfunction (EED) include plasma
citrulline (CIT), and the kynurenine (KYN): tryptophan (TRP)/(KT) ratio. We sought to …

Combating Childhood Infections in LMICs: Evaluating the contribution of Big Data Big data, biomarkers and proteomics: Informing childhood diarrhoeal disease …

KH Keddy, S Saha, IN Okeke, JB Kalule, FN Qamar… - …, 2021 - thelancet.com
Despite efforts to reduce the global burden of childhood diarrhoea, 50% of all cases globally
occur in children under five years in Low–Income and Middle-Income Countries (LMICs) and …

Prolonged Fasting Induces Histological and Ultrastructural Changes in the Intestinal Mucosa That May Reduce Absorption and Revert after Enteral Refeeding

G Nunes, M Guimarães, H Coelho, R Carregosa… - Nutrients, 2023 - mdpi.com
Background: Malnutrition is usual in patients referred for endoscopic gastrostomy (PEG).
Refeeding syndrome is rarely observed in PEG-fed patients, which could possibly be …

[HTML][HTML] Weight-for-Height Z-score gain during inpatient treatment and subsequent linear growth during outpatient treatment of young children with severe acute …

JGK Kamugisha, B Lanyero… - Current Developments …, 2021 - Elsevier
Background Linear catch-up growth after treatment of severe acute malnutrition (SAM) is
low, and little is known about the association between ponderal and subsequent linear …