Tau is a protein that is highly enriched in neurons and was originally defined by its ability to
bind and stabilize microtubules. However, it is now becoming evident that the functions of …

Highlights•SAXS captures architecture and dynamics to elucidate molecular
ensembles.•SAXS advances now probe key thermodynamic and kinetic properties of …

Proper organization and dynamics of the actin and microtubule (MT) cytoskeleton are
essential for growth cone behaviors during axon growth and guidance. The MT-associated …

Exposure of cells to colloidal nanoparticles (NPs) can have concentration-dependent
harmful effects. Mostly, such effects are monitored with biochemical assays or probes from …

Our bodies are in constant motion and so are the neurons that invade each tissue. Motion-
induced neuron deformation and damage are associated with several neurodegenerative …

The broad range of applications of synchrotron and neutron scattering in the investigation of
soft condensed matter is reviewed. Appropriate combinations of these techniques allow …

The etiology of Tauopathies, a diverse class of neurodegenerative diseases associated with
the Microtubule Associated Protein (MAP) Tau, is usually described by a common …

Scaffolded DNA origami nanostructures enable the self-assembly of arbitrarily shaped
objects with unprecedented accuracy. Yet, varying physiological conditions are prone to …

The stability and dynamics of cytoskeleton in brain nerve cells are regulated by microtubule
associated proteins (MAPs), tau and MAP2. Both proteins are intrinsically disordered and …

Tau is an intrinsically disordered protein with an important role in maintaining the dynamic
instability of neuronal microtubules. Despite intensive study, a detailed understanding of the …