Role of macroautophagy in mammalian male reproductive physiology

D Kirat, AM Alahwany, AH Arisha, A Abdelkhalek… - Cells, 2023 - mdpi.com
Physiologically, autophagy is an evolutionarily conserved and self-degradative process in
cells. Autophagy carries out normal physiological roles throughout mammalian life …

The germ cell-specific RNA binding protein RBM46 is essential for spermatogonial differentiation in mice

NJ Peart, TA Johnson, S Lee, MJ Sears, F Yang… - PLoS …, 2022 - journals.plos.org
Control over gene expression is exerted, in multiple stages of spermatogenesis, at the post-
transcriptional level by RNA binding proteins (RBPs). We identify here an essential role in …

17α-estradiol does not adversely affect sperm parameters or fertility in male mice: implications for reproduction-longevity trade-offs

JVV Isola, GB Veiga, CRC de Brito… - Geroscience, 2023 - Springer
Abstract 17α-estradiol (17α-E2) is referred to as a nonfeminizing estrogen that was recently
found to extend healthspan and lifespan in male, but not female, mice. Despite an …

Rapamycin ameliorates radiation-induced testis damage in mice

J Yang, R Xu, Y Luan, H Fan, S Yang, J Liu… - Frontiers in cell and …, 2022 - frontiersin.org
Male infertility is an important problem in human and animal reproduction. The testis is the
core of male reproduction, which is very sensitive to radiation. The decline of male …

Differential responsiveness of spermatogonia to retinoic acid dictates precocious differentiation but not meiotic entry during steady-state spermatogenesis

TA Johnson, BA Niedenberger, O Kirsanov… - Biology of …, 2023 - academic.oup.com
The foundation of mammalian spermatogenesis is provided by undifferentiated
spermatogonia, which comprise of spermatogonial stem cells (SSCs) and transit-amplifying …

Zika virus disrupts the barrier structure and Absorption/Secretion functions of the epididymis in mice

Z Sheng, N Gao, D Fan, N Wu, Y Zhang… - PLoS Neglected …, 2021 - journals.plos.org
Several studies have demonstrated that Zika virus (ZIKV) damages testis and leads to
infertility in mice; however, the infection in the epididymis, another important organ of male …

Morphology of the male rat gonad after in Utero exposure to immunosuppressants

M Freus, J Kabat-Koperska, I Frulenko… - Reproductive …, 2023 - Elsevier
The protocol for immunosuppression of pregnant women is based on immunosuppressant
panels. The aim of the study was to determine the influence of commonly applied …

[PDF][PDF] The germ cell-specific RNA binding protein RBM46 is essential for spermatogonial differentiation in mice

TA Johnson, CB Geyer - 2022 - thescholarship.ecu.edu
Control over gene expression is exerted, in multiple stages of spermatogenesis, at the
posttranscriptional level by RNA binding proteins (RBPs). We identify here an essential role …

Pharmacological Treatment of Neonatal and Juvenile Mice to Study Spermatogenesis

O Kirsanov, CB Geyer - Spermatogonial Stem Cells: Methods and …, 2023 - Springer
The delivery, to newborn and juvenile mice, of drugs and other compounds that manipulate
the physiology or cellular/molecular state-eg, by activating or inhibiting signaling pathways) …

[图书][B] Investigating Mechanisms Regulating Mammalian Spermatogonial Differentiation and Meiotic Initiation

O Kirsanov - 2022 - search.proquest.com
Spermatogonia differentiation and meiotic initiation are complex processes essential for
male fertility. Despite knowing for nearly 60 years that retinoic acid (RA) is instrumental for …