Progressive neuronal demise is a key contributor to the key pathogenic event implicated in
many different neurodegenerative disorders (NDDs). There are several therapeutic …

Our previous studies have indicated that heliox preconditioning (HePC) may exert
neuroprotective effects on neonatal hypoxic-ischemic encephalopathy (HIE). The present …

Alzheimer's Disease (AD), a neurodegenerative disorder with high incidence and mortality,
is leading its way to the top of the list of the deadliest diseases without an effective disease …

Cyclosporine is a potent immunosuppressive agent used to treat immune‐mediated
disorders in dogs. Secondary infections sometimes necessitate withdrawal of cyclosporine …

Background Dogs are often adminstered> 1 immunosuppressive medication when treating
immune‐mediated diseases, and determining whether these different medications affect IL …

Dantrolene sodium (Da) is an effective skeletal muscle relaxant. However, its
pharmacological effects are severely limited owing to its poor solubility and low oral …

Adjunctive drugs can be broadly described as drugs that fall outside common clinical use
but may provide a benefit beyond that of more commonly used drugs or are less readily …

Objective To describe a population of dogs with hops toxicosis, including clinical signs
observed, treatments performed, patient outcome, and overall prognosis. Clinical findings …

OBJECTIVE To determine the effect of dantrolene premedication on various cardiovascular
and biochemical variables and recovery in isoflurane-anesthetized horses. ANIMALS 6 …

The established analytical method for determining the concentration of dantrolene sodium
(Da) in rat tissues by HPLC/MS/MS technique was successfully applied to tissue distribution …