Recent advances in understanding the pathogenesis of rheumatoid arthritis: new treatment strategies

AL Mueller, Z Payandeh, N Mohammadkhani… - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

Curcumin and rheumatoid arthritis: A systematic review of literature

F Pourhabibi‐Zarandi… - … Journal of Clinical …, 2021 - Wiley Online Library
Background Curcumin is a natural polyphenol and the main compound from the rhizome of
Turmeric (Curcuma longa) and other Curcuma species. It has been widely used for different …

Anti-inflammatory effect of different curcumin preparations on adjuvant-induced arthritis in rats

I Rinkunaite, E Simoliunas, M Alksne… - … medicine and therapies, 2021 - Springer
Background Curcumin, a natural polyphenolic substance, has been known for more than
two millennia as having strong anti-inflammatory activity towards multiple ailments, including …

Transdermal delivery of tofacitinib citrate via mannose-decorated transferosomes loaded with tofacitinib citrate in arthritic joints

A Mahmoud, M Rady, M Abdel-Halim… - Molecular …, 2024 - ACS Publications
Transdermal drug delivery systems are a promising option for the treatment of rheumatoid
arthritis (RA) because they can lower systemic adverse effects of immunosuppressants …

Effectiveness of Curcuma longa extract versus placebo for the treatment of knee osteoarthritis: A systematic review and meta‐analysis of randomized controlled trials

W Dai, W Yan, X Leng, J Chen, X Hu… - Phytotherapy …, 2021 - Wiley Online Library
The aim of this systematic review was to evaluate the efficacy and safety of all types of
Curcuma longa extract versus placebo for knee osteoarthritis (OA) treatment. The research …

A bioavailable form of curcumin, in combination with vitamin-D-and omega-3-enriched diet, modifies disease onset and outcomes in a murine model of collagen …

M Hemshekhar, V Anaparti, H El-Gabalawy… - Arthritis Research & …, 2021 - Springer
Abstract Objective Curcumin (CUR), vitamin D 3 (D3), and omega-3-fatty acids (O3FA)
individually modulate inflammation and pain in arthritis. Although these supplements are …

Macrophage polarization towards M2 phenotype by curcuminoids through NF-κB pathway inhibition in adjuvant-induced arthritis

SS Abd-Elhalem, MH Al-Doori, MT Hassen - International …, 2023 - Elsevier
Macrophage polarization is decisive for homeostasis maintenance and tissue repair. Anti-
inflammatory properties of curcumin (CUR) have been demonstrated in several studies. It …

Evaluation of curcumin assistance in the antimicrobial and photocatalytic activity of a carbon based TiO 2 nanocomposite

V Suba, M Saravanabhavan, LS Krishna… - New Journal of …, 2020 - pubs.rsc.org
The present study focuses on the synthesis of visible light active curcumin supported
TiO2/AC (curcumin–TiO2/AC) through sol–gel and wet impregnation methods for the …

A Comparative Study of CFA and MIA Induction Models in Rat Knee Arthritis

R Normasari, B Purwanto, D Tinduh - Pharmacognosy Journal, 2023 - phcogj.com
This study presents another comparative review of knee joint arthritis induction in rats using
two distinct methods: Complete Freund's Adjuvant (CFA) and monosodium iodoacetate …

Anti-Inflammatory, Wound Healing, and Anti-Diabetic Effects of Pure Active Compounds Present in the Ryudai Gold Variety of Curcuma longa

MZ Islam, J Akter, MA Hossain, MS Islam, P Islam… - Molecules, 2024 - mdpi.com
Turmeric (Curcuma longa) contains curcumin, demethoxycurcumin (DMC), and
bisdemethoxycurcumin (BDMC). Nevertheless, curcumin is the most researched active …