[HTML][HTML] Extracellular vesicle-based drug delivery systems for cancer treatment
Extracellular vesicles (EVs) are naturally occurring cell-secreted nanoparticles that play
important roles in many physiological and pathological processes. EVs enable intercellular …
important roles in many physiological and pathological processes. EVs enable intercellular …
Clinical cancer nanomedicine
J Wolfram, M Ferrari - Nano today, 2019 - Elsevier
Nanotechnology offers new solutions for the development of cancer therapeutics that display
improved efficacy and safety. Although several nanotherapeutics have received clinical …
improved efficacy and safety. Although several nanotherapeutics have received clinical …
Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …
Tangential flow filtration for highly efficient concentration of extracellular vesicles from large volumes of fluid
Concentration of extracellular vesicles (EVs) from biological fluids in a scalable and
reproducible manner represents a major challenge. This study reports the use of tangential …
reproducible manner represents a major challenge. This study reports the use of tangential …
Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
Exosomes derived from human adipose mesenchymal stem cells ameliorate hepatic fibrosis by inhibiting PI3K/Akt/mTOR pathway and remodeling choline …
Z Zhang, J Shang, Q Yang, Z Dai, Y Liang, C Lai… - Journal of …, 2023 - Springer
Liver fibrosis is a chronic liver disease with the presence of progressive wound healing
response caused by liver injury. Currently, there are no approved therapies for liver fibrosis …
response caused by liver injury. Currently, there are no approved therapies for liver fibrosis …
Clinical translation of extracellular vesicles
Extracellular vesicles (EVs) occur in a variety of bodily fluids and have gained recent
attraction as natural materials due to their bioactive surfaces, internal cargo, and role in …
attraction as natural materials due to their bioactive surfaces, internal cargo, and role in …
[HTML][HTML] The development of mesenchymal stem cell therapy in the present, and the perspective of cell-free therapy in the future
Y Watanabe, A Tsuchiya, S Terai - Clinical and molecular …, 2021 - ncbi.nlm.nih.gov
Cirrhosis is a chronic condition that can lead to liver failure. Currently, the viable option for
decreasing mortality is liver transplantation. However, transplant surgery is highly invasive …
decreasing mortality is liver transplantation. However, transplant surgery is highly invasive …
Biogenesis, composition and potential therapeutic applications of mesenchymal stem cells derived exosomes in various diseases
YG Yuan, JL Wang, YX Zhang, L Li… - International Journal …, 2023 - Taylor & Francis
Exosomes are nanovesicles with a wide range of chemical compositions used in many
different applications. Mesenchymal stem cell-derived exosomes (MSCs-EXOs) are …
different applications. Mesenchymal stem cell-derived exosomes (MSCs-EXOs) are …
BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling
R Zuo, M Liu, Y Wang, J Li, W Wang, J Wu… - Stem cell research & …, 2019 - Springer
Background Radiotherapy to cancer patients is inevitably accompanied by normal tissue
injury, and the bone is one of the most commonly damaged tissues. Damage to bone …
injury, and the bone is one of the most commonly damaged tissues. Damage to bone …