[HTML][HTML] Extracellular vesicle-based drug delivery systems for cancer treatment

S Walker, S Busatto, A Pham, M Tian, A Suh… - Theranostics, 2019 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are naturally occurring cell-secreted nanoparticles that play
important roles in many physiological and pathological processes. EVs enable intercellular …

Clinical cancer nanomedicine

J Wolfram, M Ferrari - Nano today, 2019 - Elsevier
Nanotechnology offers new solutions for the development of cancer therapeutics that display
improved efficacy and safety. Although several nanotherapeutics have received clinical …

Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

MC Bruno, MC Cristiano, C Celia, N d'Avanzo… - ACS …, 2022 - ACS Publications
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

Tangential flow filtration for highly efficient concentration of extracellular vesicles from large volumes of fluid

S Busatto, G Vilanilam, T Ticer, WL Lin, DW Dickson… - Cells, 2018 - mdpi.com
Concentration of extracellular vesicles (EVs) from biological fluids in a scalable and
reproducible manner represents a major challenge. This study reports the use of tangential …

Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives

S Regmi, S Pathak, JO Kim, CS Yong… - European journal of cell …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

Exosomes derived from human adipose mesenchymal stem cells ameliorate hepatic fibrosis by inhibiting PI3K/Akt/mTOR pathway and remodeling choline …

Z Zhang, J Shang, Q Yang, Z Dai, Y Liang, C Lai… - Journal of …, 2023 - Springer
Liver fibrosis is a chronic liver disease with the presence of progressive wound healing
response caused by liver injury. Currently, there are no approved therapies for liver fibrosis …

Clinical translation of extracellular vesicles

A Ghodasara, A Raza, J Wolfram… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) occur in a variety of bodily fluids and have gained recent
attraction as natural materials due to their bioactive surfaces, internal cargo, and role in …

[HTML][HTML] The development of mesenchymal stem cell therapy in the present, and the perspective of cell-free therapy in the future

Y Watanabe, A Tsuchiya, S Terai - Clinical and molecular …, 2021 - ncbi.nlm.nih.gov
Cirrhosis is a chronic condition that can lead to liver failure. Currently, the viable option for
decreasing mortality is liver transplantation. However, transplant surgery is highly invasive …

Biogenesis, composition and potential therapeutic applications of mesenchymal stem cells derived exosomes in various diseases

YG Yuan, JL Wang, YX Zhang, L Li… - International Journal …, 2023 - Taylor & Francis
Exosomes are nanovesicles with a wide range of chemical compositions used in many
different applications. Mesenchymal stem cell-derived exosomes (MSCs-EXOs) are …

BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling

R Zuo, M Liu, Y Wang, J Li, W Wang, J Wu… - Stem cell research & …, 2019 - Springer
Background Radiotherapy to cancer patients is inevitably accompanied by normal tissue
injury, and the bone is one of the most commonly damaged tissues. Damage to bone …