Mammalian lipid droplets (LDs) are specialized cytosolic organelles consisting of a neutral
lipid core surrounded by a membrane made up of a phospholipid monolayer and a specific …

Fat infiltration in skeletal muscle (also known as myosteatosis) is now recognized as a
distinct disease from sarcopenia and is directly related to declining muscle capacity. Hence …

Mammalian developmental timing is adjustable in vivo by preserving pre-implantation
embryos in a dormant state called diapause. Inhibition of the growth regulator mTOR …

Lipid droplets (LDs), once considered mere storage depots for lipids, have gained
recognition for their intricate roles in cellular processes, including metabolism, membrane …

Development is regulated by various factors, including protein methylation status. While
PRMT5 is well known for its roles in oncogenesis by mediating symmetric di-methylation of …

Lipid droplets are the essential organelle for storing lipids in a cell. Within the variety of the
human body, different cells store, utilize and release lipids in different ways, depending on …

Lower-extremity peripheral arterial disease (PAD) has increased in prevalence, yet
therapeutic development has remained stagnant. Skeletal muscle health and function has …

Different types of cells uptake fatty acids in response to different stimuli or physiological
conditions; however, little is known about context-specific regulation of fatty acid uptake …

Multiple reaction monitoring (MRM) profiling is a strategy for the exploratory analysis of small
molecules and lipids by direct sample injection, ie, without the use of chromatographic …

Lipids are critical structural and functional architects of cellular homeostasis. Change in
systemic lipid profile is a clinical indicator of underlying metabolic pathologies, and …