The role of sex in the genomics of human complex traits
Nearly all human complex traits and disease phenotypes exhibit some degree of sex
differences, including differences in prevalence, age of onset, severity or disease …
differences, including differences in prevalence, age of onset, severity or disease …
A user guide to the Brassica 60K Illumina Infinium™ SNP genotyping array
Abstract The Brassica napus 60K Illumina Infinium™ SNP array has had huge international
uptake in the rapeseed community due to the revolutionary speed of acquisition and ease of …
uptake in the rapeseed community due to the revolutionary speed of acquisition and ease of …
[HTML][HTML] Long COVID or post COVID-19 syndrome
SARS-COV-2 is now recognized to be responsible not only for a lung condition but a multi-
organ syndrome (Ramakrishnan et al., 2021). After the initial acute infection, like many other …
organ syndrome (Ramakrishnan et al., 2021). After the initial acute infection, like many other …
Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium
Genotyping arrays are a cost effective approach when typing previously-identified genetic
polymorphisms in large numbers of samples. One limitation of genotyping arrays with rare …
polymorphisms in large numbers of samples. One limitation of genotyping arrays with rare …
Illumina human exome genotyping array clustering and quality control
With the rise of high-throughput sequencing technology, traditional genotyping arrays are
gradually being replaced by sequencing technology. Against this trend, Illumina has …
gradually being replaced by sequencing technology. Against this trend, Illumina has …
zCall: a rare variant caller for array-based genotyping: genetics and population analysis
JI Goldstein, A Crenshaw, J Carey, GB Grant… - …, 2012 - academic.oup.com
zCall is a variant caller specifically designed for calling rare single-nucleotide
polymorphisms from array-based technology. This caller is implemented as a post …
polymorphisms from array-based technology. This caller is implemented as a post …
How to include chromosome X in your genome‐wide association study
In current genome‐wide association studies (GWAS), the analysis is usually focused on
autosomal variants only, and the sex chromosomes are often neglected. Recently, a number …
autosomal variants only, and the sex chromosomes are often neglected. Recently, a number …
Gene set enrichment analysis of pathophysiological pathways highlights oxidative stress in psychosis
G Pistis, J Vázquez-Bourgon, M Fournier, R Jenni… - Molecular …, 2022 - nature.com
Polygenic risk prediction remains an important aim of genetic association studies. Currently,
the predictive power of schizophrenia polygenic risk scores (PRSs) is not large enough to …
the predictive power of schizophrenia polygenic risk scores (PRSs) is not large enough to …
Misidentification of runs of homozygosity islands in cattle caused by interference with copy number variation or large intermarker distances
Background Runs of homozygosity (ROH) islands are stretches of homozygous sequence in
the genome of a large proportion of individuals in a population. Algorithms for the detection …
the genome of a large proportion of individuals in a population. Algorithms for the detection …
Understanding Mendelian errors in SNP arrays data using a Gochu Asturcelta pig pedigree: genomic alterations, family size and calling errors
KD Arias, I Álvarez, JP Gutiérrez, I Fernandez… - Scientific Reports, 2022 - nature.com
Abstract Up to 478 Gochu Asturcelta pig parents-offspring trios (61 different families) were
genotyped using the Axiom_PigHDv1 Array to identify the causes of Mendelian errors (ME) …
genotyped using the Axiom_PigHDv1 Array to identify the causes of Mendelian errors (ME) …