[HTML][HTML] Adult-Onset Still's Disease—A Complex Disease, a Challenging Treatment

LA Macovei, A Burlui, I Bratoiu, C Rezus… - International Journal of …, 2022 - mdpi.com
Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder with an unknown
cause characterized by high-spiking fever, lymphadenopathy, hepatosplenomegaly …

Expanding the spectrum of the hyperferritinemic syndrome, from pathogenic mechanisms to clinical observations, and therapeutic implications

P Ruscitti, I Di Cola, C Di Muzio, N Italiano, F Ursini… - Autoimmunity …, 2022 - Elsevier
From the introduction of hyperferritinemic syndrome concept, a growing body of evidence
has suggested the role of ferritin as a pathogenic mediator and a relevant clinical feature in …

Genetic and pharmacological targeting of GSDMD ameliorates systemic inflammation in macrophage activation syndrome

S Tang, C Yang, S Li, Y Ding, D Zhu, S Ying… - Journal of …, 2022 - Elsevier
Macrophage activation syndrome (MAS), a potentially life-threatening complication of
autoimmune/autoinflammatory diseases, is characterized by the excessive expansion and …

[HTML][HTML] The administration of methotrexate in patients with Still's disease,“real-life” findings from AIDA Network Still Disease Registry

P Ruscitti, J Sota, A Vitale, G Lopalco, F Iannone… - Seminars in arthritis and …, 2023 - Elsevier
Objectives To describe clinical characteristics of patients with Still's disease treated with
methotrexate (MTX) and to assess drug effectiveness evaluating change in disease activity …

[HTML][HTML] Biomarkers in systemic juvenile idiopathic arthritis, macrophage activation syndrome and their importance in COVID era

LM Ailioaie, C Ailioaie, G Litscher - International Journal of Molecular …, 2022 - mdpi.com
Systemic juvenile idiopathic arthritis (sJIA) and its complication, macrophage activation
syndrome (sJIA-MAS), are rare but sometimes very serious or even critical diseases of …

[HTML][HTML] Advances in attractive therapeutic approach for macrophage activation syndrome in COVID-19

S Chen, C Zhang, D Chen, L Dong, T Chang… - Frontiers in …, 2023 - frontiersin.org
Nowadays, people have relaxed their vigilance against COVID-19 due to its declining
infection numbers and attenuated virulence. However, COVID-19 still needs to be concern …

[HTML][HTML] The spectrum of still's disease: a comparative analysis of phenotypic forms in a cohort of 238 patients

PA Neau, T El-Jammal, C Javaux, N Fournier… - Journal of Clinical …, 2022 - mdpi.com
Still's disease (SD) is a heterogeneous autoinflammatory disorder for which several
phenotypes have been described. We conducted a retrospective study to re-evaluate the …

Heterogeneity of macrophage activation syndrome and treatment progression

Y Dong, T Wang, H Wu - Frontiers in Immunology, 2024 - frontiersin.org
Macrophage activation syndrome (MAS) is a rare complication of autoimmune inflammatory
rheumatic diseases (AIIRD) characterized by a progressive and life-threatening condition …

[HTML][HTML] Evaluation of Glycosylated Ferritin in Adult-Onset Still's Disease and Differential Diagnoses

A Guerber, E Garneret, T El Jammal, S Zaepfel… - Journal of Clinical …, 2022 - mdpi.com
Glycosylated ferritin (GF) has been reported as a good diagnostic biomarker for adult-onset
Still's disease (AOSD), but only a few studies have validated its performance. We performed …

[HTML][HTML] Clinical and laboratory features associated with macrophage activation syndrome in Still's disease: data from the international AIDA Network Still's Disease …

P Triggianese, A Vitale, G Lopalco… - Internal and Emergency …, 2023 - Springer
To characterize clinical and laboratory signs of patients with Still's disease experiencing
macrophage activation syndrome (MAS) and identify factors associated with MAS …