[HTML][HTML] Synthesis methods of 1, 2, 3-/1, 2, 4-triazoles: A review
J Dai, S Tian, X Yang, Z Liu - Frontiers in Chemistry, 2022 - frontiersin.org
Triazole, comprising three nitrogen atoms and two carbon atoms, is divided into two isomers
1, 2, 3-triazole and 1, 2, 4-triazole. Compounds containing a triazole are one of the …
1, 2, 3-triazole and 1, 2, 4-triazole. Compounds containing a triazole are one of the …
Recent advances in pyridine scaffold: Focus on chemistry, synthesis, and antibacterial activities
MB Islam, MI Islam, N Nath, TB Emran… - BioMed research …, 2023 - Wiley Online Library
Multidrug‐resistant (MDR) pathogens have created a fatal problem for human health and
antimicrobial treatment. Among the currently available antibiotics, many are inactive against …
antimicrobial treatment. Among the currently available antibiotics, many are inactive against …
The 1, 2, 3-triazole 'all-in-one'ring system in drug discovery: A good bioisostere, a good pharmacophore, a good linker, and a versatile synthetic tool
ABSTRACT Introduction The 1, 2, 3-triazole ring occupies an important space in medicinal
chemistry due to its unique structural properties, synthetic versatility and pharmacological …
chemistry due to its unique structural properties, synthetic versatility and pharmacological …
1, 2, 3-Triazole-containing hybrids with potential antibacterial activity against ESKAPE pathogens
C Deng, H Yan, J Wang, K Liu, B Liu, Y Shi - European Journal of …, 2022 - Elsevier
ESKAPE pathogens, as priority 1 and 2 pathogens, are prevalent infectious agents
associated with high morbidity and mortality. ESKAPE can cause broad-spectrum diseases …
associated with high morbidity and mortality. ESKAPE can cause broad-spectrum diseases …
[HTML][HTML] Recent gene selection and drug resistance underscore clinical adaptation across Candida species
MÀ Schikora-Tamarit, T Gabaldón - Nature Microbiology, 2024 - nature.com
Understanding how microbial pathogens adapt to treatments, humans and clinical
environments is key to infer mechanisms of virulence, transmission and drug resistance …
environments is key to infer mechanisms of virulence, transmission and drug resistance …
Synergistic organoboron/palladium catalysis for regioselective N-allylations of azoles with allylic alcohols
A method for regioselective palladium-catalyzed allylic alkylation of ambident nitrogen
heterocycles, employing simple allylic alcohols as electrophile precursors, is described. An …
heterocycles, employing simple allylic alcohols as electrophile precursors, is described. An …
Quantitative investigation into the role of intermolecular interactions in crystalline fluorinated triazoles
A detailed study on the investigation of noncovalent interactions in the role of building
supramolecular networks and quantification of various intermolecular interactions have …
supramolecular networks and quantification of various intermolecular interactions have …
[HTML][HTML] 1, 2, 3-Triazoles and their metal chelates with antimicrobial activity
The emergence of drug-resistant bacterial and fungal pathogens has highlighted the urgent
need of innovative antimicrobial therapeutics. Transition metal complexes with biologically …
need of innovative antimicrobial therapeutics. Transition metal complexes with biologically …
[HTML][HTML] Heterocyclic compounds as synthetic tyrosinase inhibitors: recent advances
Tyrosinase is a copper-containing enzyme which is widely distributed in nature (eg, bacteria,
mammals, fungi) and involved in two consecutive steps of melanin biosynthesis. In humans …
mammals, fungi) and involved in two consecutive steps of melanin biosynthesis. In humans …
[HTML][HTML] Synthesis of novel pyrazolone candidates with studying some biological activities and in-silico studies
MH Abdellattif, EO Hamed, NKR Elhoseni, MG Assy… - Scientific reports, 2023 - nature.com
Pyranopyrazole derivatives have a vital role in the class of organic compounds because of
their broad spectrum of biological and pharmacological importance. Our current goal is the …
their broad spectrum of biological and pharmacological importance. Our current goal is the …