Iminosugars comprise the most attractive class of carbohydrate mimetics reported to date
and are ideally positioned to take advantage of our increasing understanding of …

Iminosugars are naturally occurring carbohydrate analogues known since 1967. These
natural compounds and hundreds of their synthetic derivatives prepared over five decades …

Publisher Summary The understanding of the role of carbohydrates, their receptors, and
their handling processes in the functioning of biological systems is an area in which major …

Inhibition of carbohydrate processing enzymes is a topic of great interest, as these enzymes
are involved in a plethora of key biochemical events, such as digestion, lysosomal …

This review covers the literature in the past 15 years on glycosidase inhibitors lacking a
basic nitrogen (for example iminosugars/azasugars) with a focus on natural terpenoids, and …

Background The pharmacologic modulatory effects of the antibiotic, tunicamycin (TM), on
multidrug-resistant human UWOV2 ovarian cancer cells are reported. The UWOV2 cell line …

The chemoenzymatic synthesis of a collection of pyrrolidine‐type iminosugars generated by
the aldol addition of dihydroxyacetone phosphate (DHAP) to C‐α‐substituted N‐Cbz‐2 …

In this article we review our work over the years on carbohydrates and carbohydrate
mimetics and their applications in medicinal chemistry. In the first part of the review …

We have recently found that D (−) lentiginosine, a synthetic iminosugar exerting glucosidase
inhibitory activity, but not its natural enantiomer lentiginosine, is endowed with an …

3, 4-Anhydro hexopyranosides have been prepared by diastereoselective epoxidation of
derivatives of 2-propyl 3, 4-dideoxy-α-d-erythro-hex-3-enopyranoside (5), selectively …