Pharmacology of heparin and related drugs

B Mulloy, J Hogwood, E Gray, R Lever, CP Page - Pharmacological reviews, 2016 - ASPET
Heparin has been recognized as a valuable anticoagulant and antithrombotic for several
decades and is still widely used in clinical practice for a variety of indications. The …

[HTML][HTML] Human immunodeficiency virus and heparan sulfate: from attachment to entry inhibition

BJ Connell, H Lortat-Jacob - Frontiers in immunology, 2013 - frontiersin.org
By targeting cells that provide protection against infection, HIV-1 causes acquired
immunodeficiency syndrome. Infection starts when gp120, the viral envelope glycoprotein …

Grading the commercial optical biosensor literature—Class of 2008:'The Mighty Binders'

RL Rich, DG Myszka - Journal of Molecular Recognition: An …, 2010 - Wiley Online Library
Optical biosensor technology continues to be the method of choice for label‐free, real‐time
interaction analysis. But when it comes to improving the quality of the biosensor literature …

Comparative bioinformatics analysis of the mammalian and bacterial glycomes

A Adibekian, P Stallforth, ML Hecht, DB Werz… - Chemical …, 2011 - pubs.rsc.org
A comparative analysis of bacterial and mammalian glycomes based on the statistical
analysis of two major carbohydrate databases, Bacterial CarbohydrateStructure Data Base …

Revisiting dengue virus–host cell interaction: new insights into molecular and cellular virology

EG Acosta, A Kumar, R Bartenschlager - Advances in virus research, 2014 - Elsevier
Dengue virus (DENV) is an emerging mosquito-borne human pathogen that affects millions
of individuals each year by causing severe and potentially fatal syndromes. Despite intense …

The role of heparan sulfate proteoglycans as an attachment factor for rabies virus entry and infection

M Sasaki, PD Anindita, N Ito… - The Journal of …, 2018 - academic.oup.com
Rabies virus (RABV) is the causative agent of fatal neurological disease. Cellular
attachment is the initial and essential step for viral infections. Although extensive studies …

[HTML][HTML] Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells

A Ceballos, FR Lenicov, J Sabatté… - The Journal of …, 2009 - ncbi.nlm.nih.gov
Semen is the main vector for HIV-1 dissemination worldwide. It contains three major sources
of infectious virus: free virions, infected leukocytes, and spermatozoa-associated virions. We …

Tenascin-C is an innate broad-spectrum, HIV-1–neutralizing protein in breast milk

GG Fouda, FH Jaeger, JD Amos, C Ho… - Proceedings of the …, 2013 - National Acad Sciences
Achieving an AIDS-free generation will require elimination of postnatal transmission of HIV-1
while maintaining the nutritional and immunologic benefits of breastfeeding for infants in …

A synthetic CD4–heparan sulfate glycoconjugate inhibits CCR5 and CXCR4 HIV-1 attachment and entry

F Baleux, L Loureiro-Morais, Y Hersant… - Nature chemical …, 2009 - nature.com
Abstract The HIV-1 envelope, gp120, which features the binding determinants for both CD4
and coreceptor recognition, is key for virus entry and represents an attractive …

HIV-1 Entry in SupT1-R5, CEM-ss, and Primary CD4+ T Cells Occurs at the Plasma Membrane and Does Not Require Endocytosis

N Herold, M Anders-Ößwein, B Glass… - Journal of …, 2014 - Am Soc Microbiol
Cytoplasmic entry of HIV-1 requires binding of the viral glycoproteins to the cellular receptor
and coreceptor, leading to fusion of viral and cellular membranes. Early studies suggested …