Emerging anti-spike monoclonal antibodies against SARS-CoV-2
EE Ordaya, RR Razonable - Expert Opinion on Biological Therapy, 2024 - Taylor & Francis
Introduction Anti-spike monoclonal antibodies (mAbs) were previously authorized for the
prevention and treatment of COVID-19 in immunocompromised patients. However, they are …
prevention and treatment of COVID-19 in immunocompromised patients. However, they are …
Safety and efficacy of inhaled IBIO123 for mild-to-moderate COVID-19: a randomised, double-blind, dose-ascending, placebo-controlled, phase 1/2 trial
B Maranda, SM Labbé, M Lurquin… - The Lancet Infectious …, 2024 - thelancet.com
Background COVID-19 severity is associated with its respiratory manifestations. Neutralising
antibodies against SARS-CoV-2 administered systemically have shown clinical efficacy …
antibodies against SARS-CoV-2 administered systemically have shown clinical efficacy …
Bioluminescence imaging reveals enhanced SARS-CoV-2 clearance in mice with combinatorial regimens
I Ullah, F Escudie, I Scandale, Z Gilani… - Iscience, 2024 - cell.com
Direct acting antivirals (DAAs) represent critical tools for combating severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) that have escaped …
syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) that have escaped …
The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11
WD Tolbert, Y Chen, L Sun, M Benlarbi, S Ding… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2, the virus behind the COVID-19 pandemic, has changed over time to the extent
that the current virus is substantially different from what originally led to the pandemic in …
that the current virus is substantially different from what originally led to the pandemic in …
Differentiating Cell Entry Potentials of SARS-CoV-2 Omicron Subvariants on Human Lung Epithelium Cells
The surface spike (S) glycoprotein mediates cell entry of SARS-CoV-2 into the host through
fusion at the plasma membrane or endocytosis. Omicron lineages/sublineages have …
fusion at the plasma membrane or endocytosis. Omicron lineages/sublineages have …
Combinatorial regimens augment drug monotherapy for SARS-CoV-2 clearance in mice
I Ullah, F Escudie, I Scandale, Z Gilani… - bioRxiv, 2023 - biorxiv.org
Direct acting antivirals (DAAs) represent critical tools for combating SARS-CoV-2 variants of
concern (VOCs) that evolve to escape spike-based immunity and future coronaviruses with …
concern (VOCs) that evolve to escape spike-based immunity and future coronaviruses with …