[HTML][HTML] Liquid chromatography–tandem mass spectrometry for clinical diagnostics
Mass spectrometry is a powerful analytical tool used for the analysis of a wide range of
substances and matrices; it is increasingly utilized for clinical applications in laboratory …
substances and matrices; it is increasingly utilized for clinical applications in laboratory …
Ambient ionization mass spectrometry: recent developments and applications
The early 2000s brought a new age in the field of mass spectrometry (MS) with the
introduction of ambient ionization MS techniques. As defined by one of its early visionaries …
introduction of ambient ionization MS techniques. As defined by one of its early visionaries …
Detection of ovarian cancer via the spectral fingerprinting of quantum-defect-modified carbon nanotubes in serum by machine learning
Serum biomarkers are often insufficiently sensitive or specific to facilitate cancer screening
or diagnostic testing. In ovarian cancer, the few established serum biomarkers are highly …
or diagnostic testing. In ovarian cancer, the few established serum biomarkers are highly …
[HTML][HTML] Advances in solid phase microextraction and perspective on future directions
N Reyes-Garces, E Gionfriddo… - Analytical …, 2017 - ACS Publications
Solid phase microextraction (SPME) is a versatile, nonex-haustive sample preparation tool
that has been demonstrated to be well-suited for facile and effective analysis of a broad …
that has been demonstrated to be well-suited for facile and effective analysis of a broad …
[HTML][HTML] Machine learning of serum metabolic patterns encodes early-stage lung adenocarcinoma
Early cancer detection greatly increases the chances for successful treatment, but available
diagnostics for some tumours, including lung adenocarcinoma (LA), are limited. An ideal …
diagnostics for some tumours, including lung adenocarcinoma (LA), are limited. An ideal …
Three-dimensional histological electrophoresis enables fast automatic distinguishment of cancer margins and lymph node metastases
F Zhang, J Xu, Y Yue, Y Wang, J Sun, D Song… - Science …, 2023 - science.org
Tissue diagnosis is important during surgical excision of solid tumors for margin evaluation.
Conventional histopathologic methods rely heavily on image-based visual diagnosis by …
Conventional histopathologic methods rely heavily on image-based visual diagnosis by …
5‐ALA in the management of malignant glioma
H Stepp, W Stummer - Lasers in surgery and medicine, 2018 - Wiley Online Library
Background Patients suffering from malignant gliomas have a poor prognosis. For the
surgical treatment of these tumors, 5‐aminolevulinic acid (5‐ALA) has become a new …
surgical treatment of these tumors, 5‐aminolevulinic acid (5‐ALA) has become a new …
AND-gate contrast agents for enhanced fluorescence-guided surgery
Surgical resection of tumours requires precisely locating and defining the margins between
lesions and normal tissue. However, this is made difficult by irregular margin borders …
lesions and normal tissue. However, this is made difficult by irregular margin borders …
Ambient ionization mass spectrometry today and tomorrow: embracing challenges and opportunities
Ambient ionization mass spectrometry (AIMS) has grown into a group of emerging analytical
techniques that allow rapid, real-time, high-throughput, in situ, and in vivo analysis in many …
techniques that allow rapid, real-time, high-throughput, in situ, and in vivo analysis in many …