[HTML][HTML] Liquid chromatography–tandem mass spectrometry for clinical diagnostics

SN Thomas, D French, PJ Jannetto… - Nature Reviews …, 2022 - nature.com
Mass spectrometry is a powerful analytical tool used for the analysis of a wide range of
substances and matrices; it is increasingly utilized for clinical applications in laboratory …

Ambient ionization mass spectrometry: recent developments and applications

CL Feider, A Krieger, RJ DeHoog… - Analytical chemistry, 2019 - ACS Publications
The early 2000s brought a new age in the field of mass spectrometry (MS) with the
introduction of ambient ionization MS techniques. As defined by one of its early visionaries …

Detection of ovarian cancer via the spectral fingerprinting of quantum-defect-modified carbon nanotubes in serum by machine learning

M Kim, C Chen, P Wang, JJ Mulvey, Y Yang… - Nature Biomedical …, 2022 - nature.com
Serum biomarkers are often insufficiently sensitive or specific to facilitate cancer screening
or diagnostic testing. In ovarian cancer, the few established serum biomarkers are highly …

[HTML][HTML] Advances in solid phase microextraction and perspective on future directions

N Reyes-Garces, E Gionfriddo… - Analytical …, 2017 - ACS Publications
Solid phase microextraction (SPME) is a versatile, nonex-haustive sample preparation tool
that has been demonstrated to be well-suited for facile and effective analysis of a broad …

[HTML][HTML] Machine learning of serum metabolic patterns encodes early-stage lung adenocarcinoma

L Huang, L Wang, X Hu, S Chen, Y Tao, H Su… - Nature …, 2020 - nature.com
Early cancer detection greatly increases the chances for successful treatment, but available
diagnostics for some tumours, including lung adenocarcinoma (LA), are limited. An ideal …

Three-dimensional histological electrophoresis enables fast automatic distinguishment of cancer margins and lymph node metastases

F Zhang, J Xu, Y Yue, Y Wang, J Sun, D Song… - Science …, 2023 - science.org
Tissue diagnosis is important during surgical excision of solid tumors for margin evaluation.
Conventional histopathologic methods rely heavily on image-based visual diagnosis by …

5‐ALA in the management of malignant glioma

H Stepp, W Stummer - Lasers in surgery and medicine, 2018 - Wiley Online Library
Background Patients suffering from malignant gliomas have a poor prognosis. For the
surgical treatment of these tumors, 5‐aminolevulinic acid (5‐ALA) has become a new …

[PDF][PDF] Wang

Y Wang - Jia Z, Yi Q, Song L. The various components implied …, 2018 - tranassoc.com
Systems and methods are disclosed for communicating data in an integrated sensor network
having one or more nodes coupled to an optical sensor network and a radio frequency …

AND-gate contrast agents for enhanced fluorescence-guided surgery

JC Widen, M Tholen, JJ Yim, A Antaris… - Nature biomedical …, 2021 - nature.com
Surgical resection of tumours requires precisely locating and defining the margins between
lesions and normal tissue. However, this is made difficult by irregular margin borders …

Ambient ionization mass spectrometry today and tomorrow: embracing challenges and opportunities

TH Kuo, EP Dutkiewicz, J Pei, CC Hsu - Analytical chemistry, 2019 - ACS Publications
Ambient ionization mass spectrometry (AIMS) has grown into a group of emerging analytical
techniques that allow rapid, real-time, high-throughput, in situ, and in vivo analysis in many …