Impact of plant extracts on hepatic redox metabolism upon lead exposure: a systematic review of preclinical in vivo evidence

ALF Destro, P da Silva Mattosinhos, RD Novaes… - … Science and Pollution …, 2023 - Springer
The liver is a central target organ of heavy metals toxicity, and secondary metabolites of
several plant species are suggested to attenuate lead (Pb)-induced hepatotoxicity through …

[HTML][HTML] Hepatorenal protective efficacy of flavonoids from Ocimum basilicum extract in diabetic albino rats: A focus on hypoglycemic, antioxidant, anti-inflammatory …

MS Othman, AM Khaled, AH Al-Bagawi… - Biomedicine & …, 2021 - Elsevier
Plant derived phytochemical therapy is a bright candidate for treatment of diabetes and its
associated complications. Ocimum baslicum is used as an anti-diabetic traditional medicine …

Phytochemical analysis, antioxidant, anti-inflammatory, anti-genotoxic, and anticancer activities of different Ocimum plant extracts prepared by ultrasound-assisted …

KM Anusmitha, M Aruna, JT Job… - … and Molecular Plant …, 2022 - Elsevier
The genus Ocimum belonging to the family Lamiaceae, have been widely used in traditional
medicines for the management of inflammation, dysentery, and chronic diarrhea as well as …

Neurotoxic effect of lead: a review

C Singh, A Shekhar, R Singh - Lead Toxicity: Challenges and Solution, 2023 - Springer
The neurotoxic effect of lead is a well-documented and concerning issue that poses a
significant threat to public health. Lead is a heavy metal that can accumulate in the body …

Ocimum sanctum Alters the Lipid Landscape of the Brain Cortex and Plasma to Ameliorate the Effect of Photothrombotic Stroke in a Mouse Model

I Yadav, N Sharma, R Velayudhan, Z Fatima, JS Maras - Life, 2023 - mdpi.com
Stroke-like injuries in the brain result in not only cell death at the site of the injury but also
other detrimental structural and molecular changes in regions around the stroke. A stroke …

Renal-protective effect of Asparagus officinalis aqueous extract against lead-induced nephrotoxicity mouse model

R Almeer, NM Alyami - Environmental Science and Pollution Research, 2023 - Springer
Lead is one of the cursed substances that threaten all human life. Lead poisoning can occur
through food or water contaminations and it is hard to be detected. This incognito metal …

[HTML][HTML] Amelioration of hepatotoxicity by sodium butyrate administration in rats

RM Ahmed, AK Mohammed - World's Veterinary Journal, 2022 - cyberleninka.ru
Lead poisoning is a serious environmental issue with life-threatening consequences. Lead
poisoning increases the risk of cancers, gastrointestinal disorders, hepatotoxicity, central …

A combined arsenic trioxide/tetrandrine nanoparticle formulation with improved inhibitory effect against promyelocytic leukemia

S Xu, X Zhang, X Zhu, H Su, X Yan - Journal of Drug Delivery Science and …, 2022 - Elsevier
Co-loading nanoparticles encapsulated in a copolymer carrier is a very effective strategy for
anti-tumor treatment. A combination of arsenic trioxide (ATO) and tetrandrine (TET) …

Silibinin-loaded Nanostructured Lipid Carriers (NLCs) Ameliorated Lead-induced Acute Nephrotoxicity in Male Rats

S Makhdoomi, S Ariafar, F Mirzaei… - Cell Biochemistry and …, 2024 - Springer
As a toxic heavy metal, lead (Pb) is well known for impairment of renal function due to
oxidative injuries. In contrast, the antioxidant activity of silibinin has been approved. Given …

Allium sativum Essential Oil Supplementation Reverses the Hepatic Inflammation, Genotoxicity and Apoptotic Effects in Swiss Albino Mice Intoxicated with the Lead …

K Sharma, V Sharma - Biological Trace Element Research, 2024 - Springer
Prolonged lead (Pb) exposure impairs human health due to its interference with
physiological and biochemical processes. Therefore, it is necessary to investigate natural …