Sex-hormone-binding globulin

DC Anderson - Clinical endocrinology, 1974 - pubmed.ncbi.nlm.nih.gov
PIP: A review was made to understand how plasma binding protein might influence sex-
hormone action in target tissues. Steroids are predominately bound to plasma proteins and …

The functions of corticosteroid-binding globulin and sex hormone-binding globulin: recent advances

W Rosner - Endocrine reviews, 1990 - academic.oup.com
Introduction T he presence of corticosteroid-binding globulin (CBG) in plasma was detected
about 30 yr ago, and of sex hormone-binding globulin (SHBG) about 20 yr ago. In the …

Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease

GA BURGHEN, JR GIVENS… - The Journal of Clinical …, 1980 - academic.oup.com
We evaluated basal plasma total immunoreactive insulin (insulin), androstenedione, and
testosterone in 14 obesewomen: 8 with polycystic ovarian disease (PCOD) and 6 obese …

Low serum testosterone and sex-hormone-binding-globulin in massively obese men

AR GLASS, RS SWERDLOFF, GA BRAY… - The Journal of …, 1977 - academic.oup.com
Reproductive hormonal dynamics were assessed in 10 massively obese men, 200–380% of
ideal body weight (percentage ideal body weight) and 11 similarly-aged controls who were …

Hysterectomy, oophorectomy, and endogenous sex hormone levels in older women: the Rancho Bernardo Study

GA Laughlin, E Barrett-Connor… - The Journal of …, 2000 - academic.oup.com
This study examines the cross-sectional association of hysterectomy and oophorectomy
status, chronological age, and years since menopause with plasma levels of total and …

Relationship of androgenic activity to body fat topography, fat cell morphology, and metabolic aberrations in premenopausal women

DJ Evans, RG Hoffmann, RK Kalkhoff… - The Journal of …, 1983 - academic.oup.com
A possible role for increased androgenic/estro-genic activity in the pathogenesis of upper
body fat localization and its accompanying cellular and metabolic characteristics was …

Serum testosterone levels in healthy young black and white men

R Ross, L Bernstein, H Judd, R Hanisch… - Journal of the …, 1986 - academic.oup.com
Abstract Blacks in the United States have the highest prostate cancer rate in the world and
nearly twice that of whites in the United States. The 2: 1 black-to-white ratio in prostate …

Case—control study of endogenous steroid hormones and endometrial cancer

N Potischman, RN Hoover, LA Brinton… - JNCI: Journal of the …, 1996 - academic.oup.com
Background: It has been suggested that identified risk factors for endometrial cancer operate
through a single etiologic pathway, ie, exposure to relatively high levels of unopposed …

Sex hormone binding globulin: origin, function and clinical significance

C Selby - Annals of clinical biochemistry, 1990 - journals.sagepub.com
Sex hormone binding globulin (SHBG) is a glycoprotein possessing high affinity binding for
17 β-hydroxysteriod hormones such as testosterone and oestradiol. It is probably …

Endogenous sex hormones and cardiovascular disease in men. A prospective population-based study.

E Barrett-Connor, KT Khaw - Circulation, 1988 - Am Heart Assoc
Plasma obtained and frozen in 1972-1974 from 1,009 white men (40-79 years old) who
have been followed for 12 years was examined for endogenous sex hormone levels …