Simple Summary Vimentin is an important filamentous protein providing structural and
functional support to the cell. During initial stages of cancer development, vimentin …

CD44, a non-kinase cell surface transmembrane glycoprotein, has been widely implicated
as a cancer stem cell (CSC) marker in several cancers. Cells overexpressing CD44 possess …

Navigation through the bulk tumour, entry into the blood vasculature, survival in the
circulation, exit at distant sites and resumption of proliferation are all steps necessary for …

Although cell-cycle arrest, senescence, and apoptosis are established mechanisms of tumor
suppression, accumulating evidence reveals that ferroptosis, an iron-dependent …

Cluster of differentiation 44 (CD44) is a cell surface glycoprotein overexpressed in varieties
of solid tumors including pancreatic, breast, ovary, brain, and lung cancers. It is a multi …

The cancer stem cell (CSC) hypothesis has captured the attention of many scientists. It is
believed that elimination of CSCs could possibly eradicate the whole cancer. CSC surface …

Tumor-associated macrophages (TAM) in the tumor microenvironment (TME) cooperate with
cancer stem cells (CSC) to maintain stemness. We recently identified cluster of …

Nanoparticle drug delivery systems have proved anti-tumor effects; however, they are not
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …

This work demonstrates the application of hyaluronan-conjugated nitrogen-doped carbon
quantum dots (HA-nCQDs) for bioimaging of tumor cells and illustrates their potential use as …

Background Relapse and metastasis in colorectal cancer (CRC) are often attributed to
cancer stem-like cells (CSCs), as small sub-population of tumor cells with ability of drug …