Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce
broken detailed balance at the molecular scale. This molecular scale breaking of detailed …

Catalysts open up new reaction pathways that can speed up chemical reactions while not
consuming the catalyst. A similar phenomenon has been discovered in quantum information …

Out of equilibrium, a lack of reciprocity is the rule rather than the exception. Non-reciprocity
occurs, for instance, in active matter,,,,–, non-equilibrium systems,–, networks of neurons …

Patients with primary mitochondrial oxidative phosphorylation (OxPhos) defects present with
fatigue and multi-system disorders, are often lean, and die prematurely, but the mechanistic …

For a large class of nonequilibrium systems, thermodynamic notions like work, heat, and, in
particular, entropy production can be identified on the level of fluctuating dynamical …

The principle of microscopic reversibility says that, in equilibrium, two-time cross-correlations
are symmetric under the exchange of observables. Thus, the asymmetry of cross …

Cells are the basic units of all living matter which harness the flow of energy to drive the
processes of life. While the biochemical networks involved in energy transduction are well …

Living systems operate far from thermal equilibrium by converting the chemical potential of
ATP into mechanical work to achieve growth, replication, or locomotion. Given time series …

Living systems maintain or increase local order by working against the second law of
thermodynamics. Thermodynamic consistency is restored as they consume free energy …

Brownian clocks are biomolecular networks that can count time. A paradigmatic example are
proteins that go through a cycle, thus regulating some oscillatory behavior in a living system …