Mitochondrial disorders of the OXPHOS system
E Fernandez‐Vizarra, M Zeviani - FEBS letters, 2021 - Wiley Online Library
Mitochondrial disorders are among the most frequent inborn errors of metabolism, their
primary cause being the dysfunction of the oxidative phosphorylation system (OXPHOS) …
primary cause being the dysfunction of the oxidative phosphorylation system (OXPHOS) …
[HTML][HTML] Coenzyme Q10 Supplementation in Aging and Disease
JD Hernández-Camacho, M Bernier… - Frontiers in …, 2018 - frontiersin.org
Coenzyme Q (CoQ) is an essential component of the mitochondrial electron transport chain
and an antioxidant in plasma membranes and lipoproteins. It is endogenously produced in …
and an antioxidant in plasma membranes and lipoproteins. It is endogenously produced in …
[HTML][HTML] Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7
Coenzyme Q (or ubiquinone) is a redox-active lipid that serves as universal electron carrier
in the mitochondrial respiratory chain and antioxidant in the plasma membrane limiting lipid …
in the mitochondrial respiratory chain and antioxidant in the plasma membrane limiting lipid …
[HTML][HTML] Disorders of human coenzyme Q10 metabolism: an overview
I Hargreaves, RA Heaton, D Mantle - International journal of molecular …, 2020 - mdpi.com
Coenzyme Q10 (CoQ10) has a number of vital functions in all cells, both mitochondrial and
extramitochondrial. In addition to its key role in mitochondrial oxidative phosphorylation …
extramitochondrial. In addition to its key role in mitochondrial oxidative phosphorylation …
Mitochondrial dysfunction in inherited renal disease and acute kidney injury
Mitochondria are increasingly recognized as key players in genetic and acquired renal
diseases. Most mitochondrial cytopathies that cause renal symptoms are characterized by …
diseases. Most mitochondrial cytopathies that cause renal symptoms are characterized by …
[HTML][HTML] Coenzyme Q biosynthesis in health and disease
MJ Acosta, LV Fonseca, MA Desbats, C Cerqua… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Coenzyme Q (CoQ, or ubiquinone) is a remarkable lipid that plays an essential role in
mitochondria as an electron shuttle between complexes I and II of the respiratory chain, and …
mitochondria as an electron shuttle between complexes I and II of the respiratory chain, and …
[HTML][HTML] Mitochondria related cell death modalities and disease
C Tian, Y Liu, Z Li, P Zhu, M Zhao - Frontiers in Cell and …, 2022 - frontiersin.org
Mitochondria are well known as the centre of energy metabolism in eukaryotic cells.
However, they can not only generate ATP through the tricarboxylic acid cycle and oxidative …
However, they can not only generate ATP through the tricarboxylic acid cycle and oxidative …
[HTML][HTML] Mitochondrial cardiomyopathies
AW El-Hattab, F Scaglia - Frontiers in Cardiovascular Medicine, 2016 - frontiersin.org
Mitochondria are found in all nucleated human cells and perform various essential functions,
including the generation of cellular energy. Mitochondria are under dual genome control …
including the generation of cellular energy. Mitochondria are under dual genome control …
Genetic bases and clinical manifestations of coenzyme Q10 (CoQ10) deficiency
MA Desbats, G Lunardi, M Doimo, E Trevisson… - Journal of inherited …, 2015 - Springer
Coenzyme Q 10 is a remarkable lipid involved in many cellular processes such as energy
production through the mitochondrial respiratory chain (RC), beta-oxidation of fatty acids …
production through the mitochondrial respiratory chain (RC), beta-oxidation of fatty acids …
[HTML][HTML] Coenzyme Q10 supplementation–In ageing and disease
J Aaseth, J Alexander, U Alehagen - Mechanisms of Ageing and …, 2021 - Elsevier
Abstract Coenzyme Q 10 (CoQ 10) is an essential component of the mitochondrial electron
transport chain. It is also an antioxidant in cellular membranes and lipoproteins. All cells …
transport chain. It is also an antioxidant in cellular membranes and lipoproteins. All cells …