Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits

KJ Ressler, S Berretta, VY Bolshakov… - Nature Reviews …, 2022 - nature.com
Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder,
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …

Post‐traumatic stress disorder: a state‐of‐the‐art review of evidence and challenges

RA Bryant - World psychiatry, 2019 - Wiley Online Library
Post‐traumatic stress disorder (PTSD) is arguably the most common psychiatric disorder to
arise after exposure to a traumatic event. Since its formal introduction in the DSM‐III in 1980 …

[HTML][HTML] Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan

R Pomponio, G Erus, M Habes, J Doshi, D Srinivasan… - NeuroImage, 2020 - Elsevier
As medical imaging enters its information era and presents rapidly increasing needs for big
data analytics, robust pooling and harmonization of imaging data across diverse cohorts …

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

PM Thompson, N Jahanshad, CRK Ching… - Translational …, 2020 - nature.com
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …

Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man

RJ Fenster, LAM Lebois, KJ Ressler… - Nature Reviews …, 2018 - nature.com
Post-traumatic stress disorder (PTSD) is a prevalent, debilitating and sometimes deadly
consequence of exposure to severe psychological trauma. Although effective treatments …

Neurobiology of early life adversity: A systematic review of meta-analyses towards an integrative account of its neurobiological trajectories to mental disorders

Y Hakamata, Y Suzuki, H Kobashikawa… - Frontiers in …, 2022 - Elsevier
Adverse childhood experiences (ACEs) may leave long-lasting neurobiological scars,
increasing the risk of developing mental disorders in later life. However, no review has …

Burden of environmental adversity associated with psychopathology, maturation, and brain behavior parameters in youths

RE Gur, TM Moore, AFG Rosen, R Barzilay… - JAMA …, 2019 - jamanetwork.com
Importance Low socioeconomic status (L-SES) and the experience of traumatic stressful
events (TSEs) are environmental factors implicated in behavioral deficits, abnormalities in …

The role of the immune system in posttraumatic stress disorder

S Katrinli, NCS Oliveira, JC Felger… - Translational …, 2022 - nature.com
Posttraumatic stress disorder (PTSD) develops in a subset of individuals upon exposure to
traumatic stress. In addition to well-defined psychological and behavioral symptoms, some …

ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing

L Schmaal, E Pozzi, T C. Ho, LS Van Velzen… - Translational …, 2020 - nature.com
A key objective in the field of translational psychiatry over the past few decades has been to
identify the brain correlates of major depressive disorder (MDD). Identifying measurable …

PTSD-related neuroimaging abnormalities in brain function, structure, and biochemistry

NG Harnett, AM Goodman, DC Knight - Experimental neurology, 2020 - Elsevier
Although approximately 90% of the US population will experience a traumatic event within
their lifetime, only a fraction of those traumatized individuals will develop posttraumatic …