[HTML][HTML] Comprehensive review on current developments of quinoline-based anticancer agents
S Jain, V Chandra, PK Jain, K Pathak, D Pathak… - Arabian Journal of …, 2019 - Elsevier
Among heterocyclic compounds, quinoline scaffold has become an important construction
motif for the development of new drugs. Quinoline and its derivatives possess many types of …
motif for the development of new drugs. Quinoline and its derivatives possess many types of …
Communication in the cancer microenvironment as a target for therapeutic interventions
A Dominiak, B Chełstowska, W Olejarz, G Nowicka - Cancers, 2020 - mdpi.com
The tumor microenvironment (TME) is a complex system composed of multiple cells, such as
non-cancerous fibroblasts, adipocytes, immune and vascular cells, as well as signal …
non-cancerous fibroblasts, adipocytes, immune and vascular cells, as well as signal …
An overview of privileged scaffold: quinolines and isoquinolines in medicinal chemistry as anticancer agents
Y Mao, K Soni, C Sangani, Y Yao - Current Topics in Medicinal …, 2020 - ingentaconnect.com
Cancer is one of the most difficult diseases and causes of death for many decades. Many
pieces of research are continuously going on to get a solution for cancer. Quinoline and …
pieces of research are continuously going on to get a solution for cancer. Quinoline and …
Synthesis and in vitro antiproliferative effect of novel quinoline-based potential anticancer agents
Several derivatives with a quinoline scaffold and a flexible, semi-flexible or rigid side chains
at position 8 of the quinoline ring were synthesized and assessed for their in vitro activity …
at position 8 of the quinoline ring were synthesized and assessed for their in vitro activity …
Multicomponent polymerizations of alkynes, sulfonyl azides, and 2-hydroxybenzonitrile/2-aminobenzonitrile toward multifunctional iminocoumarin/quinoline …
L Xu, T Zhou, M Liao, R Hu, BZ Tang - ACS Macro Letters, 2019 - ACS Publications
Multicomponent polymerizations (MCPs) provide a powerful synthetic tool for the
construction of polymers with complex structures and multifunctionalities, owing to their great …
construction of polymers with complex structures and multifunctionalities, owing to their great …
Using differential mobility spectrometry to measure ion solvation: an examination of the roles of solvents and ionic structures in separating quinoline-based drugs
C Liu, JCY Le Blanc, J Shields, JS Janiszewski… - Analyst, 2015 - pubs.rsc.org
Understanding the mechanisms and energetics of ion solvation is critical in many scientific
areas. Here, we present a methodlogy for studying ion solvation using differential mobility …
areas. Here, we present a methodlogy for studying ion solvation using differential mobility …
Simple and convenient preparation of novel 6, 8-disubstituted quinoline derivatives and their promising anticancer activities
A short and easy route is described for 6, 8-disubstituted derivatives of quinoline and 1, 2, 3,
4-tetrahydroquinoli-ne from 6, 8-dibromoquinolines 2 and 7 by various substitution …
4-tetrahydroquinoli-ne from 6, 8-dibromoquinolines 2 and 7 by various substitution …
Deracemization of 2-methyl-1, 2, 3, 4-tetrahydroquinoline using mutant cyclohexylamine oxidase obtained by iterative saturation mutagenesis
G Li, J Ren, P Yao, Y Duan, H Zhang, Q Wu… - ACS …, 2014 - ACS Publications
The current toolkit of biocatalysts for the production of enantiomerically pure chiral amines is
largely restricted to amine transaminases, ammonia lyases, or the genetic variants of …
largely restricted to amine transaminases, ammonia lyases, or the genetic variants of …
Gap junctions propagate opposite effects in normal and tumor testicular cells in response to cisplatin
X Hong, Q Wang, Y Yang, S Zheng, X Tong, S Zhang… - Cancer letters, 2012 - Elsevier
Gap junctions propagate toxic effects among tumor cells during chemotherapy, but could
also enhance killing of normal cells by the same mechanism. We show that the effect of gap …
also enhance killing of normal cells by the same mechanism. We show that the effect of gap …
Connexins in colorectal cancer pathogenesis
S Sirnes, GE Lind, J Bruun, TA Fykerud… - … journal of cancer, 2015 - Wiley Online Library
The connexins constitute a family of integral membrane proteins that form channels between
adjacent cells. These channels are assembled in plasma membrane domains known as gap …
adjacent cells. These channels are assembled in plasma membrane domains known as gap …